SDS-PAGE
BCL-W / BCL2L2 recombinant protein
Recombinant Human BCL-W / BCL2L2 Protein (His tag)
Gene Names
BCL2L2; BCLW; BCL-W; PPP1R51; BCL2-L-2
Purity
> 95 % as determined by SDS-PAGE
Synonyms
BCL-W / BCL2L2; Recombinant Human BCL-W / BCL2L2 Protein (His tag); BCL2L2; BCL-W; BCL2-L-2; BCLW; KIAA0271; BCL-W / BCL2L2 recombinant protein
Host
E Coli
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile 25mM Hepes 0.1MKCl 10% glycerolpH 7.5
Sequence Length
193
Application Notes
The recombinant human BCL-W consisting of 182 amino acids and has a calculated molecular mass of 20 kDa. It migrates as an approximately 18 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Met
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for BCL-W / BCL2L2 recombinant protein
Background: Beta1, 4-Galactosyltransferase-I (B4GALT1), one of seven beta1, 4-galactosyltransferases, is an enzyme commonly found in the trans-Golgi complex that adds galactose to oligosaccharides. They have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. B4GALT1 gene directs production of B4GALT1 protein using either of two transcription start sites. The product of the smaller transcript serves the traditional biosynthetic role in the Golgi. This form also complexes with alpha-lactalbumin, a mammary-specific protein, to form lactose synthase. In addition to a biosynthetic role, the protein translated from the longer transcript appears on the plasma membranes of some cells where it serves as a signalling receptor in cell-matrix interactions such as sperm-egg binding.
Description: A DNA sequence encoding the human BCL-W (Q92843-1) (Met 1-Thr 172) was fused with a polyhistidine tag at the C-terminus.
Description: A DNA sequence encoding the human BCL-W (Q92843-1) (Met 1-Thr 172) was fused with a polyhistidine tag at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
37,171 Da
NCBI Official Full Name
bcl-2-like protein 2
NCBI Official Synonym Full Names
BCL2 like 2
NCBI Official Symbol
BCL2L2
NCBI Official Synonym Symbols
BCLW; BCL-W; PPP1R51; BCL2-L-2
NCBI Protein Information
bcl-2-like protein 2
UniProt Protein Name
Bcl-2-like protein 2
UniProt Gene Name
BCL2L2
UniProt Synonym Gene Names
BCLW; KIAA0271; Bcl2-L-2
NCBI Description
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
Uniprot Description
Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.
Research Articles on BCL-W / BCL2L2
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Product Notes
The BCL-W / BCL2L2 bcl2l2 (Catalog #AAA2546557) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The recombinant human BCL-W consisting of 182 amino acids and has a calculated molecular mass of 20 kDa. It migrates as an approximately 18 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the BCL-W / BCL2L2 bcl2l2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BCL-W / BCL2L2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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