Branched Chain Aminotransferase 2 Recombinant Protein | BCAT2 recombinant protein

Recombinant Branched Chain Aminotransferase 2, Mitochondrial (BCAT2)

Cat. Num. AAA2034420

• Gene Names: BCAT2; BCAM; BCT2; PP18; BCATM
• Reactivity: Human
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >90%
• Synonyms: Branched Chain Aminotransferase 2; Recombinant Branched Chain Aminotransferase 2; Mitochondrial (BCAT2); BCAM; BCT2; PP18; BCATM; ECA40; Placental protein 18; Branched-chain-amino-acid aminotransferase; mitochondrial; BCAT2 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: >90%
• Sequence Length: 379

• Applicable Applications for BCAT2 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Tag: Two N-terminal Tags, His-tag and T7-tag
• Expression System: Prokaryotic Expression
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 48257075
• NCBI GeneID: 587
• Molecular Weight: 36.1kDa
• NCBI Official Full Name: BCAT2 protein, partial
• NCBI Official Synonym Full Names: branched chain amino acid transaminase 2
• NCBI Official Symbol: BCAT2
• NCBI Official Synonym Symbols: BCAM; BCT2; PP18; BCATM
• NCBI Protein Information: branched-chain-amino-acid aminotransferase, mitochondrial
• UniProt Protein Name: Branched-chain-amino-acid aminotransferase, mitochondrial
• UniProt Gene Name: BCAT2
• UniProt Synonym Gene Names: BCATM; BCT2; ECA40; BCAT(m); PP18
• UniProt Entry Name: BCAT2_HUMAN

NCBI Description

This gene encodes a branched chain aminotransferase found in mitochondria. The encoded protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

BCAT2: Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine. May also function as a transporter of branched chain alpha-keto acids. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. Homodimer. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Amino Acid Metabolism - valine, leucine and isoleucine biosynthesis; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 2.6.1.42; Mitochondrial; Transferase

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: mitochondrial matrix; mitochondrion

Molecular Function: branched-chain-amino-acid transaminase activity; pyridoxal phosphate binding

Biological Process: aspartate biosynthetic process; branched chain family amino acid biosynthetic process; branched chain family amino acid catabolic process; leucine biosynthetic process; valine biosynthetic process