Aurora kinase B-B (aurkb-b) Recombinant Protein | aurkb-b recombinant protein
Recombinant Xenopus laevis Aurora kinase B-B (aurkb-b)
Gene Names
aurkb.S; AurB; aik2; aim1; ark2; ipl1; stk5; airk2; stk12; AIRK2-B; aurkb-a; aurkb-b; XAIRK2-B
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Aurora kinase B-B (aurkb-b); Recombinant Xenopus laevis Aurora kinase B-B (aurkb-b); aurkb-b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-368, Full length protein
Sequence
MSYKENLIPSSCSSSSSSSSKFATPSSATAAQRVLRKQPYVSIFTTPSDNLLAQRAQLAPRVTPAASSSVPGRVALGTDVASHNTALAEAPKRKFTIDDFDIGRPLGKGKFGNVYLAREKQNKFIMALKVLFKSQLEKEGVEHQLRREIEIQSHLRHPNILRMYNYFHDRKRIYLMLEFAPRGELYKELQKHGRFDEQRSATFMEELADALQYCHERKVIHRDIKPENLLMGYKGELKIADFGWSVHAPSLRRRTMCGTLDYLPPEMIEGKTHDEKVDLWCAGVLCYEFLVGMPPFDSPSHSETHRRIVNVDLKFPPFLSEGSKDLISKLLRYHPAQRLPLKGVMEHPWVKANSRRVLPPVYQSSHPK
Sequence Length
368
Species
Xenopus laevis (African clawed frog)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42,015 Da
NCBI Official Full Name
aurora kinase B-B
NCBI Official Synonym Full Names
aurora kinase B S homeolog
NCBI Official Symbol
aurkb.S
NCBI Official Synonym Symbols
AurB; aik2; aim1; ark2; ipl1; stk5; airk2; stk12; AIRK2-B; aurkb-a; aurkb-b; XAIRK2-B
NCBI Protein Information
aurora kinase B-B
UniProt Protein Name
Aurora kinase B-B
Protein Family
UniProt Gene Name
aurkb-b
UniProt Synonym Gene Names
airk2-b; AIRK2-B; XAIRK2-B; xAurora-B-B
Uniprot Description
Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Involved in the bipolar attachment of spindle microtubules to kinetochores and is a key regulator for the onset of cytokinesis during mitosis. Required for central/midzone spindle assembly and cleavage furrow formation. Key component of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Phosphorylates 'Ser-10' of histone H3 during mitosis ().
Research Articles on aurkb-b
1. Data suggest a model in which microtubules act as scaffolds for the enzymatic activity of Aurora-B.
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Product Notes
The aurkb-b aurkb-b (Catalog #AAA1373951) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-368, Full length protein. The amino acid sequence is listed below: MSYKENLIPS SCSSSSSSSS KFATPSSATA AQRVLRKQPY VSIFTTPSDN LLAQRAQLAP RVTPAASSSV PGRVALGTDV ASHNTALAEA PKRKFTIDDF DIGRPLGKGK FGNVYLAREK QNKFIMALKV LFKSQLEKEG VEHQLRREIE IQSHLRHPNI LRMYNYFHDR KRIYLMLEFA PRGELYKELQ KHGRFDEQRS ATFMEELADA LQYCHERKVI HRDIKPENLL MGYKGELKIA DFGWSVHAPS LRRRTMCGTL DYLPPEMIEG KTHDEKVDLW CAGVLCYEFL VGMPPFDSPS HSETHRRIVN VDLKFPPFLS EGSKDLISKL LRYHPAQRLP LKGVMEHPWV KANSRRVLPP VYQSSHPK. It is sometimes possible for the material contained within the vial of "Aurora kinase B-B (aurkb-b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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