Probable two-component-system connector protein AriR (ariR) Recombinant Protein | ariR recombinant protein
Recombinant Escherichia coli Probable two-component-system connector protein AriR (ariR)
NCBI and Uniprot Product Information
NCBI Description
AriR(YmgB) is a global regulator that is upregulated by cytoplasmic pH stress (Kannan, 2008). [More information is available at EcoGene: EG14290]. AriR appears to be a regulator of acid resistance and biofilm formation. [More information is available at EcoCyc: G6606].
Uniprot Description
Probably a connector protein for RcsB/C regulation of biofilm and acid-resistance, providing additional signal input into the two-component signaling pathway. May serve to stimulate biofilm maturation, via the Rcs phosphorelay. Regulates expression of genes involved in acid-resistance and biofilm formation, including the RcsB/C two-component system. May be a non-specific DNA-binding protein that binds genes and/or intergenic regions via a geometric recognition. Also confers resistance to H2O2. Overexpression at 28 and 16 degrees Celsius increases the production of colanic acid, an exopolysaccharide and matrix component, and reduces adhesive curli fimbriae expression. Both of these effects require RcsB; AriR probably acts upstream of the RcsB/C system to stimulate the activity and not transcription of RcsB/C. 5-fluorouracil reduction in biofilm formation requires this protein.
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Product Notes
The ariR arir (Catalog #AAA1156381) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-88, full length protein. The amino acid sequence is listed below: MLEDTTIHNA ITDKALASYF RSSGNLLEEE SAVLGQAVTN LMLSGDNVNN KNIILSLIHS LETTSDILKA DVIRKTLEIV LRYTADDM. It is sometimes possible for the material contained within the vial of "Probable two-component-system connector protein AriR (ariR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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