Rat rho/rac guanine nucleotide exchange factor (GEF) 2 ELISA Kit | ARHGEF2 elisa kit
Rat Rho guanine nucleotide exchange factor 2, ARHGEF2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
ARHGEF2: a microtubule-associated guanine nucleotide exchange factor for Rac and Rho GTPases. Mediates cross-talk between microtubules and the actin cytoskeleton. Contains a phorbol esters/diacylglycerol binding and PH domain.
Protein type: GEFs, Rac/Rho; Motility/polarity/chemotaxis; GEFs
Cellular Component: Golgi apparatus; microtubule; protein complex; tight junction; focal adhesion; cell; cytoplasmic membrane-bound vesicle; cytoskeleton; cell soma; cytoplasm; spindle; dendritic shaft; vesicle
Molecular Function: Rho guanyl-nucleotide exchange factor activity; Rho GTPase binding; metal ion binding; microtubule binding; Rac guanyl-nucleotide exchange factor activity; Rac GTPase binding
Biological Process: mitosis; negative regulation of microtubule depolymerization; cell morphogenesis; positive regulation of interleukin-6 production; actin filament organization; positive regulation of tumor necrosis factor production; negative regulation of neurogenesis; activation of NF-kappaB transcription factor; positive regulation of peptidyl-tyrosine phosphorylation; establishment of mitotic spindle orientation; cell division; regulation of Rho protein signal transduction; innate immune response; positive regulation of transcription from RNA polymerase II promoter