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Arginase-2 Recombinant Protein | Arg2 recombinant protein

Recombinant Mouse Arginase-2, mitochondrial

Gene Names
Arg2; AII; AU022422
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Arginase-2; Recombinant Mouse Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase; Arg2 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
23-354aa; Full Length of Mature Protein
Sequence
VHSVAIVGAPFSRGQKKLGVEYGPAAIREAGLLKRLSRLGCHLKDFGDLSFTNVPQDDPYNNLVVYPRSVGLANQELAEVVSRAVSGGYSCVTMGGDHSLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPGFSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIGKRQRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPHLATSEEEAKATARLAVDVIASSFGQTREGGHIVYDHLPTPSSPHESENEECVRI
Production Note
Special Offer: The E Coli host-expressed protein is manufactured from a stock plasmid containing the protein gene. E Colihost-expressed protein is stocked in different unit sizes ranging from as small as 10 ug to as large as 1 mg. Bulk inventory is also available. The E Coli host-expressed protein has been ordered over and over again by researchers and has stood the test of time as both a robust protein and important target for the research community. It is part of our new program to make our most popular protein targets and corresponding hosts available in expanded unit sizes and with a quick processing time. Select E Coli host-expressed protein for the fastest delivery among all hosts. Please contact our technical support team or email to [email protected] for more details.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-Page

SDS-Page
Related Product Information for Arg2 recombinant protein
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis.
References
Cloning and characterization of the mouse and rat type II arginase genes.Iyer R.K., Bando J.M., Jenkinson C.P., Vockley J.G., Kim P.S., Kern R.M., Cederbaum S.D., Grody W.W.Mol. Genet. Metab. 63:168-175(1998) Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells.Morris S.M. Jr., Kepka-Lenhart D., Chen L.C.Am. J. Physiol. 275:E740-E747(1998) Structure of the murine arginase II gene.Shi O.U., Kepka-Lenhart D., Morris S.M. Jr., O'Brien W.E.Mamm. Genome 9:822-824(1998) Lubec G., Sunyer B., Chen W.-Q.Submitted (JAN-2009) to UniProtKB

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52.4 kDa
NCBI Official Full Name
arginase-2, mitochondrial
NCBI Official Synonym Full Names
arginase type II
NCBI Official Symbol
Arg2
NCBI Official Synonym Symbols
AII; AU022422
NCBI Protein Information
arginase-2, mitochondrial
UniProt Protein Name
Arginase-2, mitochondrial
Protein Family
UniProt Gene Name
Arg2
UniProt Entry Name
ARGI2_MOUSE

Uniprot Description

ARG2: May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. Belongs to the arginase family.

Protein type: Hydrolase; Mitochondrial; EC 3.5.3.1; Amino Acid Metabolism - arginine and proline

Cellular Component: mitochondrion

Molecular Function: arginase activity; hydrolase activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines; metal ion binding; nitric-oxide synthase binding

Biological Process: arginine catabolic process to ornithine; arginine metabolic process; negative regulation of nitric-oxide synthase activity; negative regulation of striated muscle contraction; striated muscle contraction; urea cycle

Research Articles on Arg2

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Product Notes

The Arg2 arg2 (Catalog #AAA1227644) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 23-354aa; Full Length of Mature Protein. The amino acid sequence is listed below: VHSVAIVGAP FSRGQKKLGV EYGPAAIREA GLLKRLSRLG CHLKDFGDLS FTNVPQDDPY NNLVVYPRSV GLANQELAEV VSRAVSGGYS CVTMGGDHSL AIGTIIGHAR HRPDLCVIWV DAHADINTPL TTVSGNIHGQ PLSFLIKELQ DKVPQLPGFS WIKPCLSPPN IVYIGLRDVE PPEHFILKNY DIQYFSMREI DRLGIQKVME QTFDRLIGKR QRPIHLSFDI DAFDPKLAPA TGTPVVGGLT YREGVYITEE IHNTGLLSAL DLVEVNPHLA TSEEEAKATA RLAVDVIASS FGQTREGGHI VYDHLPTPSS PHESENEECV RI . It is sometimes possible for the material contained within the vial of "Arginase-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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