Apelin receptor B (aplnrb) Recombinant Protein | aplnrb recombinant protein
Recombinant Danio rerio Apelin receptor B (aplnrb)
NCBI and Uniprot Product Information
Uniprot Description
Function: Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity
By similarity. Plays a role in gastrulation. Required for heart formation, regulating the migration of cells fated to become myocardial progenitors. Acts redundantly with agtrl1a in heart development. Ref.1 Ref.3 Ref.4 UniProtKB Q9JHG3
Subcellular location: Membrane; Multi-pass membrane protein
Potential.
Tissue specificity: Mesendodermal expression at the blastoderm margin appears by 4.5 hpf. At early gastrulation, expression is maintained ventrolaterally while expression in dorsal cells and random deep cells declines. During gastrulation and segmentation, expression is maintained in adaxial, intermediate, and lateral plate mesoderm. During late segmentation, expressed in several regions including the forming heart. By 24 hpf, expressed in the dorsal aorta, caudal vein, and intersomitic blood vessels. Ref.1
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Sequence caution: The sequence AAH97125.1 differs from that shown. Reason: Erroneous initiation.
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Product Notes
The aplnrb aplnrb (Catalog #AAA1174985) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-359. The amino acid sequence is listed below: MNAMDNMTAD YSPDYFDDAV NSSMCEYDEW EPSYSLIPVL YMLIFILGLT GNGVVIFTVW RAQSKRRAAD VYIGNLALAD LTFVVTLPLW AVYTALGYHW PFGVALCKIS SYVVLLNMYA SVFCLTCLSL DRYMAIVHSL TSTQLRTRGH MRASLTAIWL LSGVLAAPTL LFRTTVYDVE TNRTSCAMDF NLVVSQPGQE TYWIAGLSIS STALGFLIPL LAMMVCYGFI GCTVTRHFNS LRKEDQRKRR LLKIITTLVV VFAACWMPFH VVKTMDALSY LNLAPDSCTF LNLLLLAHPY ATCLAYVNSC LNPLLYAFFD LRFRSQCLCL LNLKKALHAS PASSLSSQKT EAQSLATKV. It is sometimes possible for the material contained within the vial of "Apelin receptor B (aplnrb), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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