Annexin A5 Recombinant Protein | ANXA5 recombinant protein
Recombinant Mouse Annexin A5
Sterile Filtered clear solution.
Description: ANXA5 Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 342 amino acids (1-319 a.a) and having a molecular mass of 38.1kDa.ANXA5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
NCBI and Uniprot Product Information
Uniprot Description
ANXA5: a calcium/phospholipid-binding protein and an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. The binding of labeled ANXA5 to phosphatidylserine is used as a marker of apoptosis. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.
Protein type: Apoptosis; Calcium-binding; Inhibitor; Lipid-binding
Cellular Component: cell projection; cell soma; cytoplasm; cytosol; dendrite; endoplasmic reticulum; external side of plasma membrane; extracellular space; focal adhesion; intracellular; membrane; nerve terminal; nucleus; perikaryon; plasma membrane; sarcolemma; synaptic vesicle; Z disc
Molecular Function: calcium-dependent phospholipid binding; calcium-transporting ATPase activity; peptide hormone binding; protein binding; receptor tyrosine kinase binding
Biological Process: negative regulation of blood coagulation; positive regulation of apoptosis; protein homooligomerization; response to calcium ion; response to organic substance
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Product Notes
The ANXA5 anxa5 (Catalog #AAA141073) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSP MGSMAT RGTV TDFPGFDGRA DAEVLRKAMK GLGTDEDSIL NLLTSRSNAQ RQEIAQEFKT LFGRDLVDDL KSELTGKFEK LIVAMMKPSR LYDAYELKHA LKGAGTDEKV LTEIIASRTP EELSAIKQVY EEEYGSNLED DVVGDTSGYY QRMLVVLLQA NRDPDTAIDD AQVELDAQAL FQAGELKWGT DEEKFITIFG TRSVSHLRRV FDKYMTISGF QIEETIDRET SGNLEQLLLA VVKSIRSIPA YLAETLYYAM KGAGTDDHTL IRVVVSRSEI DLFNIRKEFR KNFATSLYSM IKGDTSGDYK KALLLLCGGE DD. It is sometimes possible for the material contained within the vial of "Annexin A5, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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