Human annexin A2 ELISA Kit | ANXA2 elisa kit

Human Annexin II, ANX-II ELISA Kit

Cat. Num. AAA701012

• Gene Names: ANXA2; P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270
• Reactivity: Human
• Synonyms: annexin A2; Human Annexin II; ANX-II ELISA Kit; Human Annexin II (ANX-II) ELISA Kit; ANX2; ANX2L4; CAL1H; LIP2; LPC2; LPC2D; P36; PAP-IV; annexin II; calpactin I heavy polypeptide; chromobindin 8; lipocortin II; placental anticoagulant protein IV; ANXA2 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of human ANX-II. No significant cross-reactivity or interference between human ANX-II and analogues was observed.
• Sequence Length: 339

• Samples: Serum, urine, saliva, cell lysates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.39 ng/ml-25 ng/ml
• Sensitivity: <0.098 ng/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess.
• Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for ANXA2 elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for ANX-II has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any ANX-II present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for ANX-II is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of ANX-II bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 50845386
• NCBI GeneID: 302
• NCBI Accession #: NP_001002857.1
• NCBI GenBank Nucleotide #: NM_001002857.1
• UniProt Accession #: P07355; Q567R4; Q6N0B3; Q8TBV2; Q96DD5; Q9UDH8
• Molecular Weight: 38,604 Da
• NCBI Official Full Name: annexin A2 isoform 2
• NCBI Official Synonym Full Names: annexin A2
• NCBI Official Symbol: ANXA2
• NCBI Official Synonym Symbols: P36; ANX2; LIP2; LPC2; CAL1H; LPC2D; ANX2L4; PAP-IV; HEL-S-270
• NCBI Protein Information: annexin A2; annexin-2; protein I; annexin II; lipocortin II; chromobindin 8; chromobindin-8; calpactin I heavy chain; calpactin-1 heavy chain; calpactin I heavy polypeptide; placental anticoagulant protein IV; epididymis secretory protein Li 270
• UniProt Protein Name: Annexin A2
• Protein Family: Annexin
• UniProt Gene Name: ANXA2
• UniProt Synonym Gene Names: ANX2; ANX2L4; CAL1H; LPC2D; PAP-IV
• UniProt Entry Name: ANXA2_HUMAN

NCBI Description

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. This gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.