Western Blot (WB)
(Western blot analysis TF2L1 using HT-29 whole cell lysates)
TF2L1 Antibody | anti-TF2L1 antibody
TF2L1 Antibody
Western Blot (WB)
(Western blot analysis TF2L1 using HT-29 whole cell lysates)
Western Blot (WB)
(Western blot analysis TF2L1 using HT-29 whole cell lysates)
NCBI and Uniprot Product Information
Uniprot Description
Transcription factor that facilitates establishment and maintenance of pluripotency in embryonic stem cells (ESCs) (PubMed:25215486, PubMed:26906118). With KLF2, acts as the major effector of self-renewal that mediates induction of pluripotency downstream of LIF/STAT3 and Wnt/beta-catenin signaling (). Required for normal duct development in the salivary gland and kidney (). Coordinates the development of the kidney collecting ducts intercalated (IC) and principal (PC) cells, which regulate acid-base and salt-water homeostasis, respectively (). Regulates the expression of IC genes including subunits B1 and D2 of the V-ATPase complex, OXGR1, CA12, SLC4A1, AQP6 and IC-specific transcription factor FOXI1 (). Regulates also the expression of JAG1 and subsequent notch signaling in the collecting duct (). JAG1 initiates notch signaling in PCs but inhibits notch signaling in ICs (). Acts as a transcriptional suppressor that may suppress UBP1-mediated transcriptional activation (). Modulates the placental expression of CYP11A1 (PubMed:10644752).
Research Articles on TF2L1
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Product Notes
The TF2L1 tfcp2l1 (Catalog #AAA8513359) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "TF2L1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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