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Immunohistochemistry (Immunohistochemistry analysis of paraffin-embedded human brain tissue using SRF (Ab-77) antibody.)

SRF Antibody | anti-SRF antibody

SRF (Ab-77) Antibody

Gene Names
SRF; MCM1
Synonyms
SRF; SRF (Ab-77) Antibody; anti-SRF antibody
Ordering
For Research Use Only!
Sequence Length
304

Immunohistochemistry

(Immunohistochemistry analysis of paraffin-embedded human brain tissue using SRF (Ab-77) antibody.)

Immunohistochemistry (Immunohistochemistry analysis of paraffin-embedded human brain tissue using SRF (Ab-77) antibody.)

Western Blot

(Western blot analysis of extracts from Jurkat cells, treated with insulin (0.01U/ml, 15mins), using SRF (Ab-77) antibody.)

Western Blot (Western blot analysis of extracts from Jurkat cells, treated with insulin (0.01U/ml, 15mins), using SRF (Ab-77) antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,593 Da
NCBI Official Full Name
serum response factor isoform 2
NCBI Official Synonym Full Names
serum response factor
NCBI Official Symbol
SRF
NCBI Official Synonym Symbols
MCM1
NCBI Protein Information
serum response factor
UniProt Protein Name
Serum response factor
Protein Family
UniProt Gene Name
SRF
UniProt Synonym Gene Names
SRF

NCBI Description

This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Uniprot Description

SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentiation and maturation.

Research Articles on SRF

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Product Notes

The SRF srf (Catalog #AAA852415) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "SRF, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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