RBPMS Antibody | anti-RBPMS antibody

RBPMS Antibody

Cat. Num. AAA8503772

• Gene Names: RBPMS; HERMES
• Synonyms: RBPMS; RBPMS Antibody; anti-RBPMS antibody

• Sequence Length: 196

NCBI and Uniprot Product Information

• NCBI GI #: 57164969
• NCBI GeneID: 11030
• NCBI Accession #: NP_001008710.1
• NCBI GenBank Nucleotide #: NM_001008710.2
• UniProt Accession #: Q93062; Q92516; Q92517; Q92518; Q96J26; D3DSU9
• Molecular Weight: 17,022 Da
• NCBI Official Full Name: RNA-binding protein with multiple splicing isoform A
• NCBI Official Synonym Full Names: RNA binding protein, mRNA processing factor
• NCBI Official Symbol: RBPMS
• NCBI Official Synonym Symbols: HERMES
• NCBI Protein Information: RNA-binding protein with multiple splicing
• UniProt Protein Name: RNA-binding protein with multiple splicing
• Protein Family: RNA-binding protein with multiple splicing
• UniProt Gene Name: RBPMS
• UniProt Synonym Gene Names: HERMES; RBP-MS; Hermes

NCBI Description

This gene encodes a member of the RNA recognition motif family of RNA-binding proteins. The RNA recognition motif is between 80-100 amino acids in length and family members contain one to four copies of the motif. The RNA recognition motif consists of two short stretches of conserved sequence, as well as a few highly conserved hydrophobic residues. The encoded protein has a single, putative RNA recognition motif in its N-terminus. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

Uniprot Description

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins (PubMed:26347403). Binds to poly(A) RNA (PubMed:17099224, PubMed:26347403).