RAB22A Antibody | anti-RAB22A antibody

RAB22A Antibody

Cat. Num. AAA8518830

• Synonyms: RAB22A; RAB22A Antibody; anti-RAB22A antibody

• Sequence Length: 194

Western Blot (WB)

(Western blot analysis RAB22A using HT29 whole cell lysates)

NCBI and Uniprot Product Information

• NCBI GI #: 10190714
• NCBI GeneID: 57403
• NCBI Accession #: NP_065724.1
• NCBI GenBank Nucleotide #: NM_020673.2
• UniProt Accession #: Q9UL26; Q8TF12; Q9H4E6; B3KR86; E1P605
• Molecular Weight: 21,855 Da
• NCBI Official Full Name: ras-related protein Rab-22A
• NCBI Official Synonym Full Names: RAB22A, member RAS oncogene family
• NCBI Official Symbol: RAB22A
• NCBI Protein Information: ras-related protein Rab-22A
• UniProt Protein Name: Ras-related protein Rab-22A
• Protein Family: Ras-related protein
• UniProt Gene Name: RAB22A
• UniProt Synonym Gene Names: RAB22; Rab-22

NCBI Description

The protein encoded by this gene is a member of the RAB family of small GTPases. The GTP-bound form of the encoded protein has been shown to interact with early-endosomal antigen 1, and may be involved in the trafficking of and interaction between endosomal compartments. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes (PubMed:16537905). Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth (PubMed:21849477). Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form (PubMed:16537905).