MYO16 Antibody | anti-MYO16 antibody

MYO16 Antibody

Cat. Num. AAA8518666

• Gene Names: MYO16; MYR8; MYAP3; NYAP3; Myo16b; PPP1R107
• Synonyms: MYO16; MYO16 Antibody; anti-MYO16 antibody

• Sequence Length: 1880

Western Blot (WB)

(Western blot analysis MYO16 using Jurkat whole cell lysates)

NCBI and Uniprot Product Information

• NCBI GI #: 312147315
• NCBI GeneID: 23026
• NCBI Accession #: NP_001185879.1
• NCBI GenBank Nucleotide #: NM_001198950.2
• Molecular Weight: 82,275 Da
• NCBI Official Full Name: unconventional myosin-XVI isoform 1
• NCBI Official Synonym Full Names: myosin XVI
• NCBI Official Symbol: MYO16
• NCBI Official Synonym Symbols: MYR8; MYAP3; NYAP3; Myo16b; PPP1R107
• NCBI Protein Information: unconventional myosin-XVI
• UniProt Protein Name: Unconventional myosin-XVI
• Protein Family: Unconventional myosin
• UniProt Gene Name: MYO16

NCBI Description

This gene encodes an unconventional myosin protein. The encoded protein has been proposed to act as a serine/threonine phosphatase-1 targeting or regulatory subunit. Studies in a rat cell line suggest that this protein may regulate cell cycle progression. A variant within this gene may be associated with susceptibility to schizophrenia and elevated expression of this gene has been observed in the frontal cortex of human schizophrenia patients. [provided by RefSeq, Mar 2017]

Uniprot Description

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. May be involved in targeting of the catalytic subunit of protein phosphatase 1 during brain development. Activates PI3K and concomitantly recruits the WAVE1 complex to the close vicinity of PI3K and regulates neuronal morphogenesis ().