COQ7 Antibody | anti-COQ7 antibody

COQ7 Antibody

Cat. Num. AAA8502535

• Gene Names: COQ7; CAT5; CLK1; CLK-1; COQ10D8
• Synonyms: COQ7; COQ7 Antibody; anti-COQ7 antibody

• Sequence Length: 179

NCBI and Uniprot Product Information

• NCBI GI #: 300244542
• NCBI GeneID: 10229
• NCBI Accession #: NP_001177912.1
• NCBI GenBank Nucleotide #: NM_001190983.1
• UniProt Accession #: Q99807; Q9BTT7; Q9H0T5; Q9UEW5; Q9UNR5; B2RDA9
• Molecular Weight: 20,158 Da
• NCBI Official Full Name: 5-demethoxyubiquinone hydroxylase, mitochondrial isoform 2
• NCBI Official Synonym Full Names: coenzyme Q7, hydroxylase
• NCBI Official Symbol: COQ7
• NCBI Official Synonym Symbols: CAT5; CLK1; CLK-1; COQ10D8
• NCBI Protein Information: 5-demethoxyubiquinone hydroxylase, mitochondrial
• UniProt Protein Name: 5-demethoxyubiquinone hydroxylase, mitochondrial
• Protein Family: 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase
• UniProt Gene Name: COQ7
• UniProt Synonym Gene Names: DMQ hydroxylase

NCBI Description

The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2010]

Uniprot Description

Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.