ABCA7 Antibody | anti-ABCA7 antibody

ABCA7 Antibody

Cat. Num. AAA8518258

• Gene Names: ABCA7; AD9; ABCX; ABCA-SSN
• Synonyms: ABCA7; ABCA7 Antibody; anti-ABCA7 antibody

• Sequence Length: 2146

Western Blot (WB)

(Western blot analysis ABCA7 using Jurkat whole cell lysates)

NCBI and Uniprot Product Information

• NCBI GI #: 150417984
• NCBI GeneID: 10347
• NCBI Accession #: NP_061985.2
• NCBI GenBank Nucleotide #: NM_019112.3
• UniProt Accession #: Q8IZY2; Q96S58; Q9BZC4; Q9NR73; Q9UKP8
• Molecular Weight: 218,497 Da
• NCBI Official Full Name: ATP-binding cassette sub-family A member 7
• NCBI Official Synonym Full Names: ATP binding cassette subfamily A member 7
• NCBI Official Symbol: ABCA7
• NCBI Official Synonym Symbols: AD9; ABCX; ABCA-SSN
• NCBI Protein Information: ATP-binding cassette sub-family A member 7
• UniProt Protein Name: ATP-binding cassette sub-family A member 7
• Protein Family: ABC transporter A family
• UniProt Gene Name: ABCA7

NCBI Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This full transporter has been detected predominantly in myelo-lymphatic tissues with the highest expression in peripheral leukocytes, thymus, spleen, and bone marrow. The function of this protein is not yet known; however, the expression pattern suggests a role in lipid homeostasis in cells of the immune system. [provided by RefSeq, Jul 2008]

Uniprot Description

Plays a role in phagocytosis by macrophages of apoptotic cells. Binds APOA1 and may function in apolipoprotein-mediated phospholipid efflux from cells. May also mediate cholesterol efflux. May regulate cellular ceramide homeostasis during keratinocytes differentiation.