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Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-MSK1 (Ser376) Polyclonal Antibody at dilution of 1:1000)
p38 MAPK antibody kit
Phospho-p38 MAPK Pathway Sampler Kit
Applications
Western Blot
Synonyms
p38 MAPK; Phospho-p38 MAPK Pathway Sampler Kit; p38 MAPK antibody kit
Applicable Applications for p38 MAPK antibody kit
Western Blot (WB)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-MSK1 (Ser376) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-MSK1 (Ser376) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of various cells with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of various cells with Phospho-p38 (Thr180/Tyr182) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of Hela cells with Phospho-MEK-3 (Ser218) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of Hela cells with Phospho-MEK-3 (Ser218) Polyclonal Antibody)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-ATF-2 (Thr71) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-ATF-2 (Thr71) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-HSP27 (Ser82) Polyclonal Antibody at dilution of 1:1000)
Western Blot (WB)
(Western Blot analysis of HuvEc cells with Phospho-HSP27 (Ser82) Polyclonal Antibody at dilution of 1:1000)
Related Product Information for p38 MAPK antibody kit
Background: p38 MAP kinase (MAPK), also called RK or CSBP, is the mammalian orthologue of the yeast HOG kinase that participates in a signaling cascade controlling cellular responses to cytokines and stress. Four isoforms of p38 MAPK, p38alpha, beta, gamma (also known as Erk6 or SAPK3), and delta (also known as SAPK4) have been identified. Similar to the SAPK/JNK pathway, p38 MAPK is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharide (LPS), UV light, and growth factors (1-5). MKK3, MKK6, and SEK activate p38 MAPK by phosphorylation at Thr180 and Tyr182. Activated p38 MAPK has been shown to phosphorylate and activate MAPKAP kinase 2 and to phosphorylate the transcription factors ATF-2, Max, and MEF2. SB203580 (4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-imidazole) is a selective inhibitor of p38 MAPK. This compound inhibits the activation of MAPKAPK-2 by p38 MAPK and subsequent phosphorylation of HSP27. SB203580 inhibits p38 MAPK catalytic activity by binding to the ATP-binding pocket, but does not inhibit phosphorylation of p38 MAPK by upstream kinases.
Similar Products
Product Notes
The p38 MAPK (Catalog #AAA2549992) is an Antibody Kit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's p38 MAPK can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the p38 MAPK for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p38 MAPK, Antibody Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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