Structure
(Structure of M4693-15A Entinostat, Free Base)
MS-275 Antibiotic
MS-275 (Entinostat, SNDX-275)
Purity
Highly Purified~99%
Synonyms
MS-275; MS-275 (Entinostat; SNDX-275); MS-275 antibiotic
Purity/Purification
Highly Purified
~99%
~99%
Form/Format
Supplied as a white to off-white powder.
CAS Number
209783-80-2
Molecular Formula
C21H20N4O3
Melting Point
216-218ºC
Solubility
Soluble in DMSO at 25mg/ml with slight warming; very poorly soluble in ethanol and water; maximum solubility in plain water is estimated to be about 10-20uM. buffers, serum, or other additives may increase or decrease the aqueous solubility.
Preparation and Storage
May be stored at RT for short-term only. Long-term storage is recommended at -20 degree C. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Structure
(Structure of M4693-15A Entinostat, Free Base)
Structure
(Structure of M4693-15A Entinostat, Free Base)
Related Product Information for MS-275 antibiotic
MS-275 is a synthetic benzamide derivative that inhibited partially purified human histone deacetylase (HDA) with an IC50 of 2uM and induced hyperacetylation of nuclear histones in tumor cell lines. MS-275 inhibited the proliferation of various human tumor cell lines such as A2780, Calu-3, HL-60, and K562 (IC50 values were 0.0415uM, 0.195uM, 0.212uM, and 0.589uM, respectively). MS-275 also inhibited the growth of human tumor xenografts in nude mouse.
Product Categories/Family for MS-275 antibiotic
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
376.41
NCBI Official Full Name
maltose transport system permease protein MalF
Similar Products
Product Notes
The MS-275 (Catalog #AAA651541) is an Antibiotic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MS-275, Antibiotic" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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