Aminopeptidase N (ANPEP) Recombinant Protein | ANPEP recombinant protein

Recombinant Cat Aminopeptidase N (ANPEP), partial

• Gene Names: ANPEP; APN
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Aminopeptidase N (ANPEP); Recombinant Cat Aminopeptidase N (ANPEP); partial; ANPEP recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 967

• Species: Felis catus (Cat) (Felis silvestris catus)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for ANPEP recombinant protein

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.

NCBI and Uniprot Product Information

• NCBI GI #: 57527809
• NCBI GeneID: 493785
• NCBI Accession #: NP_001009252.2
• NCBI GenBank Nucleotide #: NM_001009252.2
• UniProt Accession #: P79171; O97783
• Molecular Weight: 109,424 Da
• NCBI Official Full Name: aminopeptidase N
• NCBI Official Symbol: ANPEP
• NCBI Official Synonym Symbols: APN
• NCBI Protein Information: aminopeptidase N
• UniProt Protein Name: Aminopeptidase N
• Protein Family: Aminopeptidase
• UniProt Gene Name: ANPEP
• UniProt Synonym Gene Names: APN; AP-N; fAPN; AP-M

Uniprot Description

Broad specificity aminopeptidase which plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Also involved in the processing of various peptides including peptide hormones, such as angiotensin III and IV, neuropeptides, and chemokines. May also be involved the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis and promote cholesterol crystallization.