ALDOC recombinant protein

Recombinant ALDOC protein

Cat. Num. AAA389350

• Gene Names: ALDOC; ALDC
• Synonyms: ALDOC; Recombinant ALDOC protein; Aldolase C; fructose-bisphosphate C; ALDOC recombinant protein

• Host: E Coli
• Form/Format: Recombinant ALDOC protein is supplied in 25mM Tris-HCl pH8.0, 300mM NaCl, 10% glycerol and 0.5mM TCEP.

• Protein Species: Human
• Tag: His-Tag
• Notes: This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for a given product is shown on the lot-specific Technical Data Sheet.
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.; Shipping Temp: Dry Ice

SDS-Page

(Recombinant ALDOC protein gel 12.5% SDS-PAGE with Coomassie blue staining MW: 40.5 kDa Purity: >92%)

Related Product Information for ALDOC recombinant protein

Short Description: Full-length human ALDOC protein was expressed in E Coli (accession number NP_005156.1) with a C-terminal 6xHis-tag. The molecular weight of the protein is 40.5 kDa.

Background: ALDOC (Aldolase, Fructose-Bisphosphate C) is a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively.

Product Categories/Family for ALDOC recombinant protein

Recombinant Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 4885063
• NCBI GeneID: 230
• NCBI Accession #: NP_005156.1
• NCBI GenBank Nucleotide #: NM_005165.2
• UniProt Accession #: P09972; Q3SYL3; Q6FH94; Q6P0L5; B2R5R3
• Molecular Weight: 39,456 Da
• NCBI Official Full Name: fructose-bisphosphate aldolase C
• NCBI Official Synonym Full Names: aldolase C, fructose-bisphosphate
• NCBI Official Symbol: ALDOC
• NCBI Official Synonym Symbols: ALDC
• NCBI Protein Information: fructose-bisphosphate aldolase C; aldolase 3; fructoaldolase C; brain-type aldolase; fructose-1,6-biphosphate triosephosphate lyase
• UniProt Protein Name: Fructose-bisphosphate aldolase C
• Protein Family: Fructose-bisphosphate aldolase
• UniProt Gene Name: ALDOC
• UniProt Synonym Gene Names: ALDC
• UniProt Entry Name: ALDOC_HUMAN

NCBI Description

This gene encodes a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Uniprot Description

ALDOC: a member of the class I fructose-biphosphate aldolase gene family. Expressed specifically in the hippocampus and Purkinje cells of the brain, the encoded protein is a glycolytic enzyme that catalyzes the reversible aldol cleavage of fructose-1,6-biphosphate and fructose 1-phosphate to dihydroxyacetone phosphate and either glyceraldehyde-3-phosphate or glyceraldehyde, respectively. [provided by RefSeq, Jul 2008]

Protein type: Carbohydrate Metabolism - glycolysis and gluconeogenesis; Carbohydrate Metabolism - pentose phosphate pathway; Lyase; Carbohydrate Metabolism - fructose and mannose; EC 4.1.2.13

Chromosomal Location of Human Ortholog: 17cen-q12

Cellular Component: cytoskeleton; mitochondrion; axon; cytosol

Molecular Function: protein binding; cytoskeletal protein binding; fructose-bisphosphate aldolase activity

Biological Process: organ regeneration; glycolysis; apoptosis; glucose metabolic process; pathogenesis; response to organic nitrogen; response to organic cyclic substance; protein homotetramerization; gluconeogenesis; fructose 1,6-bisphosphate metabolic process; epithelial cell differentiation; carbohydrate metabolic process; response to hypoxia; protein heterotetramerization; aging; fructose metabolic process