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Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1) Recombinant Protein | ALDH3A1 recombinant protein

Recombinant Dog Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1)

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Aldehyde dehydrogenase; dimeric NADP-preferring (ALDH3A1); Recombinant Dog Aldehyde dehydrogenase; ALDH3A1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-453, Full length protein
Sequence
SKISEVVQRARAAFNSGKTRPLQFRIQQLEALRRMIKEHEKDLAGALTADLHKNEWNAYYEEVVYVLEEIEYMIKKLPEWAADEPVEKTPQTQQDECYIHSEPLGVVLIIGTWNYPFTVTIQPMVGAIAAGNAVVIKPSELSENMANLLATIIPQYLDRDLYPVISGGIPETTELLKERFDHILYTGNTAVGKVIMMAAAKHLTPVTLELGGKNPCYVDKDCDLDIACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKALKEFYGEDAKKSRDYGRIINSRHFQRVMGLMEGQKVAYGGTGDAATRYIAPTILIDVDTQSQVMQEEIFGPVMPIVCVRSLEEAIQFINQREKPLALYVFSLNDKMIKKMIAETSSGGVTANDVIVHVSVHSLPYGGVGNSGMGSYHGKKSFETFSHCRSCLVRPLLNDESLKTRYPPSLAKMTRH
Sequence Length
452
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for ALDH3A1 recombinant protein
Aldehyde dehydrogenases oxidize various aldehydes to the corresponding acids. They are involved in the detoxification of alcohol-derived acetaldehyde and in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. The enzyme encoded by this gene forms a cytoplasmic homodimer that preferentially oxidizes aromatic and medium-chain (6 carbons or more) saturated and unsaturated aldehyde substrates. It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Multiple alternatively spliced variants, encoding the same protein, have been identified.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
50,713 Da
NCBI Official Full Name
aldehyde dehydrogenase, dimeric NADP-preferring
NCBI Official Synonym Full Names
aldehyde dehydrogenase 3 family member A1
NCBI Official Symbol
ALDH3A1
NCBI Protein Information
aldehyde dehydrogenase, dimeric NADP-preferring
UniProt Protein Name
Aldehyde dehydrogenase, dimeric NADP-preferring
Protein Family
UniProt Gene Name
ALDH3A1
UniProt Synonym Gene Names
ALDH3

Uniprot Description

ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (). Preferentially oxidizes aromatic aldehyde substrates (). Comprises about 50 percent of corneal epithelial soluble proteins (). May play a role in preventing corneal damage caused by ultraviolet light ().

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Product Notes

The ALDH3A1 aldh3a1 (Catalog #AAA1006605) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-453, Full length protein. The amino acid sequence is listed below: SKISEVVQRA RAAFNSGKTR PLQFRIQQLE ALRRMIKEHE KDLAGALTAD LHKNEWNAYY EEVVYVLEEI EYMIKKLPEW AADEPVEKTP QTQQDECYIH SEPLGVVLII GTWNYPFTVT IQPMVGAIAA GNAVVIKPSE LSENMANLLA TIIPQYLDRD LYPVISGGIP ETTELLKERF DHILYTGNTA VGKVIMMAAA KHLTPVTLEL GGKNPCYVDK DCDLDIACRR IAWGKFMNSG QTCVAPDYIL CDPSIQNQIV EKLKKALKEF YGEDAKKSRD YGRIINSRHF QRVMGLMEGQ KVAYGGTGDA ATRYIAPTIL IDVDTQSQVM QEEIFGPVMP IVCVRSLEEA IQFINQREKP LALYVFSLND KMIKKMIAET SSGGVTANDV IVHVSVHSLP YGGVGNSGMG SYHGKKSFET FSHCRSCLVR PLLNDESLKT RYPPSLAKMT RH. It is sometimes possible for the material contained within the vial of "Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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