Human Aldo-keto reductase family 1 member C3 ELISA Kit | AKR1C3 elisa kit
Human Aldo-keto reductase family 1 member C3 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
AKR1C3: Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta- PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone. Belongs to the aldo/keto reductase family.
Protein type: EC 1.1.1.149; Lipid Metabolism - arachidonic acid; Oxidoreductase; Xenobiotic Metabolism - metabolism by cytochrome P450
Chromosomal Location of Human Ortholog: 10p15.1
Cellular Component: cytoplasm; cytosol; intracellular; nucleus
Molecular Function: 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity; 3(or 17)-alpha-hydroxysteroid dehydrogenase activity; aldehyde reductase activity; aldo-keto reductase activity; delta4-3-oxosteroid 5beta-reductase activity; geranylgeranyl reductase activity; ketoreductase activity; ketosteroid monooxygenase activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; phenanthrene 9,10-monooxygenase activity; retinal dehydrogenase activity; retinol dehydrogenase activity
Biological Process: cellular response to starvation; cyclooxygenase pathway; farnesol catabolic process; G-protein coupled receptor protein signaling pathway; keratinocyte differentiation; male gonad development; multicellular organismal macromolecule metabolic process; positive regulation of cell proliferation; positive regulation of protein kinase B signaling cascade; progesterone metabolic process; prostaglandin metabolic process; protein import into nucleus, translocation; regulation of retinoic acid receptor signaling pathway; response to nutrient; retinal metabolic process; retinoid metabolic process; steroid metabolic process
Similar Products
Product Notes
The Human AKR1C3 akr1c3 (Catalog #AAA9428917) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9428917 ELISA Kit recognizes Human AKR1C3. It is sometimes possible for the material contained within the vial of "Aldo-keto reductase family 1 member C3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
