SDS-PAGE
Type-2 angiotensin II receptor Recombinant Protein | Agtr2 recombinant protein
Recombinant Rat Type-2 angiotensin II receptor
SDS-PAGE
SDS-PAGE
NCBI and Uniprot Product Information
NCBI Description
receptor for angiotensin II; vasodilator that regulates many actions in vascular smooth muscle cells and during development [RGD, Feb 2006]
Uniprot Description
AT2: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. Defects in AGTR2 are the cause of mental retardation X- linked type 88 (MRX88). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: integral to membrane; intracellular; perinuclear region of cytoplasm; plasma membrane
Molecular Function: angiotensin type II receptor activity; G-protein alpha-subunit binding; peptide hormone binding; protein binding; transcription factor binding
Biological Process: angiotensin mediated vasodilation involved in regulation of systemic arterial blood pressure; brain renin-angiotensin system; cell surface receptor linked signal transduction; cellular sodium ion homeostasis; cerebellar cortex development; dopamine biosynthetic process; G-protein signaling, coupled to cGMP nucleotide second messenger; inflammatory response; kidney development; negative regulation of fibroblast proliferation; negative regulation of heart rate; negative regulation of icosanoid secretion; negative regulation of nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis; neuron differentiation; positive regulation of cell proliferation; positive regulation of cytokine secretion; positive regulation of nitric-oxide synthase activity; positive regulation of phosphoprotein phosphatase activity; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; regulation of systemic arterial blood pressure by circulatory renin-angiotensin; regulation of transcription factor import into nucleus; renin-angiotensin regulation of aldosterone production; response to organic nitrogen
Research Articles on Agtr2
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Product Notes
The Agtr2 agtr2 (Catalog #AAA718350) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-45aa; Extracellular Domain. The amino acid sequence is listed below: MKDNFSFAAT SRNITSSLPF DNLNATGTNE SAFNCSHKPA DKHLE. It is sometimes possible for the material contained within the vial of "Type-2 angiotensin II receptor, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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