Mouse Type-2 angiotensin II receptor ELISA Kit | Agtr2 elisa kit
Mouse Type-2 angiotensin II receptor ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
AT2: Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. Defects in AGTR2 are the cause of mental retardation X- linked type 88 (MRX88). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Belongs to the G-protein coupled receptor 1 family.
Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass
Cellular Component: integral to membrane; membrane; perinuclear region of cytoplasm; plasma membrane
Molecular Function: angiotensin type II receptor activity; G-protein coupled receptor activity; peptide hormone binding; signal transducer activity; transcription factor binding
Biological Process: angiotensin mediated vasodilation involved in regulation of systemic arterial blood pressure; brain renin-angiotensin system; cell surface receptor linked signal transduction; cellular sodium ion homeostasis; cerebellar cortex development; dopamine biosynthetic process; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cGMP nucleotide second messenger; inflammatory response; negative regulation of fibroblast proliferation; negative regulation of heart rate; negative regulation of icosanoid secretion; negative regulation of nerve growth factor receptor signaling pathway; negative regulation of neuron apoptosis; positive regulation of cell proliferation; positive regulation of cytokine secretion; positive regulation of nitric-oxide synthase activity; positive regulation of phosphoprotein phosphatase activity; positive regulation of transcription, DNA-dependent; positive regulation of vasodilation; regulation of apoptosis; regulation of systemic arterial blood pressure by circulatory renin-angiotensin; regulation of transcription factor import into nucleus; regulation of vasodilation; renin-angiotensin regulation of aldosterone production; signal transduction
Research Articles on Agtr2
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Product Notes
The Mouse Agtr2 agtr2 (Catalog #AAA2884944) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2884944 ELISA Kit recognizes Mouse Agtr2. It is sometimes possible for the material contained within the vial of "Type-2 angiotensin II receptor, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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