Angiotensinogen (AGT) Recombinant Protein | AGT recombinant protein
Recombinant Chicken Angiotensinogen (AGT)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Angiotensinogen (AGT); Recombinant Chicken Angiotensinogen (AGT); Recombinant Angiotensinogen (AGT); Angiotensinogen; Serpin A8 Cleaved into the following 3 chains: 1. Angiotensin-1; Angiotensin I; Ang I Angiotensin-2; Angiotensin II; Ang II Angiotensin-3; Angiotensin III; Ang III Des-Asp[1]-angiotensin II; AGT recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-10aa; Full length protein
Sequence
DRVYVHPFSL
Sequence Length
10
Species
Gallus gallus (Chicken)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Related Product Information for AGT recombinant protein
This protein, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
1,232 Da
NCBI Official Full Name
Angiotensinogen
UniProt Protein Name
Angiotensinogen
Protein Family
UniProt Gene Name
AGT
UniProt Synonym Gene Names
SERPINA8; Ang I; Ang II; Ang III
UniProt Entry Name
ANGT_CHICK
Uniprot Description
Function: In response to lowered blood pressure, the enzyme renin cleaves angiotensin-1, from angiotensinogen. ACE (angiotensin converting enzyme) then removes a dipeptide to yield the physiologically active peptide angiotensin-2, the most potent pressor substance known, which helps regulate volume and mineral balance of body fluids.
Subcellular location: Secreted.
Tissue specificity: Expressed by the liver and secreted in plasma.
Sequence similarities: Belongs to the serpin family.
Research Articles on AGT
Similar Products
Product Notes
The Angiotensinogen (AGT) agt (Catalog #AAA964225) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-10aa; Full length protein. The amino acid sequence is listed below: DRVYVHPFSL. It is sometimes possible for the material contained within the vial of "Angiotensinogen (AGT), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
