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SDS-Page

AGR3 recombinant protein

AGR3 Protein, Human, Recombinant (mFc Tag)

Gene Names
AGR3; AG3; HAG3; hAG-3; BCMP11; PDIA18
Purity
>85% as determined by SDS-PAGE
Synonyms
AGR3; AGR3 Protein; Human; Recombinant (mFc Tag); Human AGR3/hAG-3/BCMP11 Protein (Fc Tag); AG-3 Protein; AG3 Protein; BCMP11 Protein; hAG-3 Protein; HAG3 Protein; PDIA18 Protein; anterior gradient 3; AGR3 recombinant protein
Ordering
For Research Use Only!
Host
HEK293 Cells
Purity/Purification
>85% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Met1-Leu166
Species
Human
Endotoxin
<1.0EU per ug protein as determined by the LAL method.
Predicted N Terminal
Ile 22
Tag
C-mouse IgG1-Fc
Protein Construction
A DNA sequence encoding the human AGR3 (NP_789783.1)(Met1-Leu166) was expressed with the Fc region of mouse IgG1 at the C-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.

SDS-Page

SDS-Page
Related Product Information for AGR3 recombinant protein
Background: Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been characterised as a novel potential biomarker both for breast cancer prognosis and early breast cancer detection from blood.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,171 Da
NCBI Official Full Name
anterior gradient protein 3 homolog
NCBI Official Synonym Full Names
anterior gradient 3 homolog (Xenopus laevis)
NCBI Official Symbol
AGR3
NCBI Official Synonym Symbols
AG3; HAG3; hAG-3; BCMP11; PDIA18
NCBI Protein Information
anterior gradient protein 3 homolog; AG-3; anterior gradient homolog 3; breast cancer membrane protein 11; protein disulfide isomerase family A, member 18
UniProt Protein Name
Anterior gradient protein 3 homolog
Protein Family
UniProt Gene Name
AGR3
UniProt Synonym Gene Names
BCMP11; AG-3; AG3; hAG-3
UniProt Entry Name
AGR3_HUMAN

Uniprot Description

AGR3: Belongs to the AGR family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7p21.1

Cellular Component: extracellular region

Molecular Function: protein binding

Research Articles on AGR3

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Product Notes

The AGR3 agr3 (Catalog #AAA8121534) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Met1-Leu16 6. It is sometimes possible for the material contained within the vial of "AGR3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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