Anterior Gradient Protein 2 Homolog Recombinant Protein | AGR2 recombinant protein
Recombinant Human Anterior Gradient Protein 2 Homolog
Gene Names
AGR2; AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Anterior Gradient Protein 2 Homolog; Recombinant Human Anterior Gradient Protein 2 Homolog; AGR2 Human; Anterior Gradient Protein 2 Homolog Human Recombinant; Anterior gradient protein 2 homolog; Secreted cement gland protein XAG-2 homolog; AG-2; hAG-2; HPC8; AGR2; AG2; GOB-4; HAG-2; XAG-2; AGR2 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The protein contains 20mM Tris-HCl pH 8.0, 1mM DTT, 1mM EDTA and 10% Glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL
Sequence Length
175
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for AGR2 recombinant protein
Description: Anterior Gradient Protein 2 Homolog Human Recombinant fused to His-tag on N-terminal produced in E Coli is a single, non-glycosylated polypeptide chain containing 192 amino acids (21-175) & having a molecular mass of 22 kDa.
Introduction: AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.
Introduction: AGR2 (Anterior gradient 2 homolog) is the human orthologue of the secreted Xenopus laevis Anterior Gradient protein (XAG-2). This is a small, possibly secreted molecule of yet weakly defined functions that is widely expressed in human tissues. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of EGF receptor.
Product Categories/Family for AGR2 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
19,979 Da
NCBI Official Full Name
anterior gradient protein 2 homolog
NCBI Official Synonym Full Names
anterior gradient 2
NCBI Official Symbol
AGR2
NCBI Official Synonym Symbols
AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116
NCBI Protein Information
anterior gradient protein 2 homolog; AG-2; HPC8; anterior gradient homolog 2; epididymis secretory protein Li 116; protein disulfide isomerase family A, member 17; secreted cement gland homolog; secreted cement gland protein XAG-2 homolog
UniProt Protein Name
Anterior gradient protein 2 homolog
Protein Family
UniProt Gene Name
AGR2
UniProt Synonym Gene Names
AG2; AG-2; hAG-2
UniProt Entry Name
AGR2_HUMAN
Uniprot Description
AGR2: Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells. Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth. Interacts with LYPD3 and DAG1 (alphaDAG1). Interacts with MUC2; disulfide-linked. Expressed strongly in trachea, lung, stomach, colon, prostate and small intestine. Expressed weakly in pituitary gland, salivary gland, mammary gland, bladder, appendix, ovary, fetal lung, uterus, pancreas, kidney, fetal kidney, testis, placenta, thyroid gland and in estrogen receptor (ER)-positive breast cancer cell lines. Belongs to the AGR family.
Protein type: Secreted, signal peptide; Secreted; Oncoprotein
Chromosomal Location of Human Ortholog: 7p21.3
Cellular Component: mitochondrion; endoplasmic reticulum; extracellular region
Molecular Function: protein binding
Research Articles on AGR2
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Product Notes
The AGR2 agr2 (Catalog #AAA143130) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRDT TVKPGAKKDT KDSRPKLPQT LSRGWGDQLI WTQTYEEALY KSKTSNKPLM IIHHLDECPH SQALKKVFAE NKEIQKLAEQ FVLLNLVYET TDKHLSPDGQ YVPRIMFVDP SLTVRADITG RYSNRLYAYE PADTALLLDN MKKALKLLKT EL. It is sometimes possible for the material contained within the vial of "Anterior Gradient Protein 2 Homolog, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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