Protein argonaute-3 (EIF2C3) Recombinant Protein | EIF2C3 recombinant protein

Recombinant Bovine Protein argonaute-3 (EIF2C3) , partial

• Gene Names: AGO3; EIF2C3
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Protein argonaute-3 (EIF2C3); Recombinant Bovine Protein argonaute-3 (EIF2C3); partial; EIF2C3 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 861

• Species: Bovine
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for EIF2C3 recombinant protein

This gene encodes a member of the Argonaute family of proteins which play a role in RNA interference. The encoded protein is highly basic, contains a PAZ domain and a PIWI domain, and may play a role in short-interfering-RNA-mediated gene silencing. This gene is located on chromosome 1 in a tandem cluster of closely related family members including argonaute 4 and eukaryotic translation initiation factor 2C, 1. Two transcript variants encoding distinct isoforms have been identified for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 229544700
• NCBI GeneID: 406231
• UniProt Accession #: Q6T5B7
• Molecular Weight: 97,300 Da
• NCBI Official Full Name: Protein argonaute-3
• NCBI Official Symbol: AGO3
• NCBI Official Synonym Symbols: EIF2C3
• NCBI Protein Information: protein argonaute-3
• UniProt Protein Name: Protein argonaute-3
• UniProt Gene Name: AGO3
• UniProt Synonym Gene Names: EIF2C3; Argonaute3; eIF-2C 3; eIF2C 3

Uniprot Description

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4 ().