Neurotoxin-2 Recombinant Protein | AFII recombinant protein
Recombinant Anthopleura fuscoviridis Neurotoxin-2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Neurotoxin-2; Recombinant Anthopleura fuscoviridis Neurotoxin-2; AFII recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-48, Full length protein
Sequence
GGVPCLCDSDGPSVRGNTLSGIIWLAGCPSGWHNCKAHGPTIGWCCKQ
Sequence Length
48
Species
Anthopleura fuscoviridis (Sea anemone)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
4,941 Da
NCBI Official Full Name
Delta-actitoxin-Afv1b
UniProt Protein Name
Delta-actitoxin-Afv1b
Protein Family
UniProt Gene Name
AFII
UniProt Synonym Gene Names
AFII
Uniprot Description
Binds specifically to voltage-gated sodium channels (Nav), thereby delaying their inactivation. This toxin has a great efficacy for Nav1.4/SCN4A (EC(50)=30.62 nM) and Nav1.5/SCN5A (EC(50)=62.5 nM). It is less potent on Nav1.6/SCN8A (EC(50)=about 300 nM), Nav1.1/SCN1A (EC(50)=390.55 nM), Nav1.3/SCN3A (EC(50)=459.36 nM) and Nav1.2/SCN2A (EC(50)=1998.00 nM) (when measured as the increase in the slow component).
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Product Notes
The Neurotoxin-2 afii (Catalog #AAA1058692) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-48, Full length protein. The amino acid sequence is listed below: GGVPCLCDSD GPSVRGNTLS GIIWLAGCPS GWHNCKAHGP TIGWCCKQ. It is sometimes possible for the material contained within the vial of "Neurotoxin-2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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