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SDS-PAGE

Proteasomal ubiquitin receptor ADRM1 Recombinant Protein | ADRM1 recombinant protein

Recombinant Human Proteasomal ubiquitin receptor ADRM1

Gene Names
ADRM1; ARM1; ARM-1; GP110
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Proteasomal ubiquitin receptor ADRM1; Recombinant Human Proteasomal ubiquitin receptor ADRM1; Homo sapiens (Human); ADRM1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-407aa; Full Length
Sequence
TTSGALFPSLVPGSRGASNKYLVEFRAGKMSLKGTTVTPDKRKGLVYIQQTDDSLIHFCWKDRTSGNVEDDLIIFPDDCEFKRVPQCPSGRVYVLKFKAGSKRLFFWMQEPKTDQDEEHCRKVNEYLNNPPMPGALGASGSSGHELSALGGEGGLQSLLGNMSHSQLMQLIGPAGLGGLGGLGALTGPGLASLLGSSGPPGSSSSSSSRSQSAAVTPSSTTSSTRATPAPSAPAAASATSPSPAPSSGNGASTAASPTQPIQLSDLQSILATMNVPAGPAGGQQVDLASVLTPEIMAPILANADVQERLLPYLPSGESLPQTADEIQNTLTSPQFQQALGMFSAALASGQLGPLMCQFGLPAEAVEAANKGDVEAFAKAMQNNAKPEQKEGDTKDKKDEEEDMSLD
Sequence Length
368
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for ADRM1 recombinant protein
Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity.
Product Categories/Family for ADRM1 recombinant protein
References
"A novel proteasome-interacting protein recruits the deubiquitinating enzyme UCH37 to 26S proteasomes." Hamazaki J., Iemura S., Natsume T., Yashiroda H., Tanaka K., Murata S. EMBO J. 25:4524-4536(2006)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
58 kDa
NCBI Official Full Name
proteasomal ubiquitin receptor ADRM1 isoform 2
NCBI Official Synonym Full Names
adhesion regulating molecule 1
NCBI Official Symbol
ADRM1
NCBI Official Synonym Symbols
ARM1; ARM-1; GP110
NCBI Protein Information
proteasomal ubiquitin receptor ADRM1
UniProt Protein Name
Proteasomal ubiquitin receptor ADRM1
UniProt Gene Name
ADRM1
UniProt Synonym Gene Names
GP110; Gp110; ARM-1; hRpn13
UniProt Entry Name
ADRM1_HUMAN

NCBI Description

This gene encodes a member of the adhesion regulating molecule 1 protein family. The encoded protein is a component of the proteasome where it acts as a ubiquitin receptor and recruits the deubiquitinating enzyme, ubiquitin carboxyl-terminal hydrolase L5. Increased levels of the encoded protein are associated with increased cell adhesion, which is likely an indirect effect of this intracellular protein. Dysregulation of this gene has been implicated in carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Uniprot Description

ADRM1: Functions as a proteasomal ubiquitin receptor. Recruits the deubiquitinating enzyme UCHL5 at the 26S proteasome and promotes its activity. Interacts with PSMD1, ubiquitin and UCHL5. Belongs to the ADRM1 family.

Protein type: Cell development/differentiation; Proteasome complex

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cytoplasm; integral to plasma membrane; membrane; nucleoplasm; plasma membrane; proteasome complex

Molecular Function: protease binding; protein binding

Biological Process: proteasome assembly; RNA elongation from RNA polymerase II promoter

Research Articles on ADRM1

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Product Notes

The ADRM1 adrm1 (Catalog #AAA1301947) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-407aa; Full Length. The amino acid sequence is listed below: TTSGALFPSL VPGSRGASNK YLVEFRAGKM SLKGTTVTPD KRKGLVYIQQ TDDSLIHFCW KDRTSGNVED DLIIFPDDCE FKRVPQCPSG RVYVLKFKAG SKRLFFWMQE PKTDQDEEHC RKVNEYLNNP PMPGALGASG SSGHELSALG GEGGLQSLLG NMSHSQLMQL IGPAGLGGLG GLGALTGPGL ASLLGSSGPP GSSSSSSSRS QSAAVTPSST TSSTRATPAP SAPAAASATS PSPAPSSGNG ASTAASPTQP IQLSDLQSIL ATMNVPAGPA GGQQVDLASV LTPEIMAPIL ANADVQERLL PYLPSGESLP QTADEIQNTL TSPQFQQALG MFSAALASGQ LGPLMCQFGL PAEAVEAANK GDVEAFAKAM QNNAKPEQKE GDTKDKKDEE EDMSLD. It is sometimes possible for the material contained within the vial of "Proteasomal ubiquitin receptor ADRM1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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