(Rhesus macaque) Beta-1 adrenergic receptor (ADRB1) Recombinant Protein | ADRB1 recombinant protein
Recombinant Macaca mulatta (Rhesus macaque) Beta-1 adrenergic receptor (ADRB1)
NCBI and Uniprot Product Information
Uniprot Description
Function: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity.
Subunit structure: Interacts with GOPC, MAGI3 and DLG4
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein
By similarity. Note: Localized at the plasma membrane. Found in the Golgi upon GOPC overexpression
By similarity.
Domain: The PDZ domain-binding motif mediates competitive interactions with GOPC, MAGI3 and DLG4 and plays a role in subcellular location of the receptor
By similarity.
Post-translational modification: Homologous desensitization of the receptor is mediated by its phosphorylation by beta-adrenergic receptor kinase.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRB1 sub-subfamily.
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Product Notes
The (Rhesus macaque) Beta-1 adrenergic receptor (ADRB1) adrb1 (Catalog #AAA961165) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-480. The amino acid sequence is listed below: MGAGALVLGA SEPGNLSSAA PLPDGVATAA RLLVPASPPA SLLPPASEGP EPLSQQWTAG MGLLMALIVL LIVAGNVLVI VAIAKTPRLQ TLTNLFIMSL ASADLVMGLL VVPFGATIVV WGRWEYGSFF CELWTSVDVL CVTASIETLC VIALDRYLAI TSPFRYQSLL TRARARGLVC TVWAISALVS FLPILMHWWR AESDEARRCY NDPKCCDFVT NRAYAIASSV VSFYVPLCIM AFVYLRVFRE AQKQVKKIDS CERRFLGGPA RPPSPSPSPS PSPVPAPPPG PPRPAAAAAT TAPLVNGRAG KRRPSRLVAL REQKALKTLG IIMGVFTLCW LPFFLANVVK AFHRELVPDR LFVFFNWLGY ANSAFNPIIY CRSPDFRNAF QRLLCCARRA ARRRHAAHGD RPRASGCLAR PGPPPSPGAA SDDDDDDVVG ATQPARLLEP WAGCNGGAAA DSDSSLDEPC RPGFASESKV. It is sometimes possible for the material contained within the vial of "(Rhesus macaque) Beta-1 adrenergic receptor (ADRB1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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