Loading...

Skip to main content

Call us on + 1 (800) 604-9114 for more information about our products

Looking for specific datasheet Manual/COA/MSDS?
Request a Manual/COA/MSDS

Interested to get a quote about our products?
Request a Quote

Gene Sequencing (extract)

Adrenomedullin 2 Recombinant Protein | ADM2 recombinant protein

Recombinant Adrenomedullin 2 (ADM2)

Gene Names
ADM2; AM2; dJ579N16.4
Reactivity
Homo sapiens (Human)
Applications
SDS-Page, Western Blot
Purity
> 95%
Synonyms
Adrenomedullin 2; Recombinant Adrenomedullin 2 (ADM2); ADM2 recombinant protein
Ordering
For Research Use Only!
Host
E.coli
Reactivity
Homo sapiens (Human)
Purity/Purification
> 95%
Form/Format
20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.
Concentration
Original Concentration: 80ug/mL (varies by lot)
Sequence
TQAQLLRVGC VLGTCQVQNL SHRLWQLMGP AGRQDSAPVD PSSPHSY
Applicable Applications for ADM2 recombinant protein
Positive Control, Immunogen, SDS-PAGE, Western Blot (WB)
(May be suitable for use in other assays to be determined by the end users.)
Source
Prokaryotic expression
Residues
Thr101~Tyr147
Tags
N-terminal His Tag
Subcellular Location
Secreted
Traits
Freeze-dried powder
Predicted isoelectric point
8.2
Phenomenon explanation
The possible reasons that the actual band size differs from the predicted are as follows:
1. Splice variants: Alternative splicing may create different sized proteins from the same gene.
2. Relative charge: The composition of amino acids may affects the charge of the protein.
3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.
4. Post-translation cleavage: Many proteins are synthesized as pro-proteins, and then cleaved to give the active form.
5. Polymerization of the target protein: Dimerization, multimerization etc.
Usage
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
Preparation and Storage
Storage:
Avoid repeated freeze/thaw cycles.
Store at 2-8°C for one month.
Aliquot and store at -80°C for 12 months.

Stability Test:
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Gene Sequencing (extract)

Gene Sequencing (extract)

SDS-PAGE

SDS-PAGE
Product Categories/Family for ADM2 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein ADM2 preproprotein
NCBI Official Synonym Full Names
adrenomedullin 2
NCBI Official Symbol
ADM2
NCBI Official Synonym Symbols
AM2; dJ579N16.4
NCBI Protein Information
protein ADM2
UniProt Protein Name
ADM2
Protein Family
ADM
UniProt Gene Name
ADM2
UniProt Synonym Gene Names
AM2; AM2; IMDL; IMDS

NCBI Description

This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. [provided by RefSeq, Jul 2015]

Uniprot Description

ADM2: IMDL and IMDS may play a role as physiological regulators of gastrointestinal, cardiovascular bioactivities mediated by the CALCRL/RAMPs receptor complexes. Activates the cAMP-dependent pathway. Belongs to the adrenomedullin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: extracellular region; intracellular

Molecular Function: hormone activity; protein complex binding

Biological Process: adenylate cyclase-activating G-protein coupled receptor signaling pathway; angiogenesis; digestion; feeding behavior; negative regulation of blood pressure; positive regulation of angiogenesis; protein amino acid phosphorylation

Research Articles on ADM2

Similar Products

Product Notes

The ADM2 adm2 (Catalog #AAA2123890) is a Recombinant Protein produced from E.coli and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Adrenomedullin 2 (ADM2) reacts with Homo sapiens (Human) and may cross-react with other species as described in the data sheet. AAA Biotech's Adrenomedullin 2 can be used in a range of immunoassay formats including, but not limited to, Positive Control, Immunogen, SDS-PAGE, Western Blot (WB) (May be suitable for use in other assays to be determined by the end users.). Researchers should empirically determine the suitability of the ADM2 adm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: TQAQLLRVGC VLGTCQVQNL SHRLWQLMGP AGRQDSAPVD PSSPHSY. It is sometimes possible for the material contained within the vial of "Adrenomedullin 2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

Item has been added to Shopping Cart

If you are ready to order, navigate to Shopping Cart and get ready to checkout.

Looking for a specific manual?
Request a Manual

Request more Information

Please complete the form below and a representative will contact you as soon as possible.

Request a Manual

Please complete the form below and a representative will contact you as soon as possible.

Request a Quote

Please complete the form below and a representative will contact you as soon as possible.