Human alcohol dehydrogenase 5 (class III) , chi polypeptide ELISA Kit | ADH5 elisa kit
Human Alcohol dehydrogenase class-3, ADH5 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
Uniprot Description
ADH5: Class-III ADH is remarkably ineffective in oxidizing ethanol, but it readily catalyzes the oxidation of long-chain primary alcohols and the oxidation of S-(hydroxymethyl) glutathione. Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
Protein type: Xenobiotic Metabolism - metabolism by cytochrome P450; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Oxidoreductase; EC 1.1.1.1; Mitochondrial; EC 1.1.1.284; Energy Metabolism - methane; Cofactor and Vitamin Metabolism - retinol; Lipid Metabolism - fatty acid; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - tyrosine
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: mitochondrion; nucleus
Molecular Function: protein homodimerization activity; electron carrier activity; zinc ion binding; formaldehyde dehydrogenase activity; S-(hydroxymethyl)glutathione dehydrogenase activity; alcohol dehydrogenase activity; fatty acid binding
Biological Process: respiratory system process; response to nitrosative stress; ethanol catabolic process; formaldehyde catabolic process; peptidyl-cysteine S-nitrosylation; response to lipopolysaccharide; response to redox state; retinoid metabolic process; ethanol oxidation; positive regulation of blood pressure; aging
Research Articles on ADH5
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Product Notes
The Human ADH5 adh5 (Catalog #AAA9342234) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9342234 ELISA Kit recognizes Human ADH5. It is sometimes possible for the material contained within the vial of "alcohol dehydrogenase 5 (class III) , chi polypeptide, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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