Typical Testing Data/Standard Curve (for reference only)
Human A disintegrin and metalloproteinase with thrombospondin motifs 7 ELISA Kit | ADAMTS7 elisa kit
Human A disintegrin and metalloproteinase with thrombospondin motifs 7 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
Uniprot Description
ADAMTS7: Metalloprotease that may play a role in the degradation of COMP.
Protein type: Secreted; Motility/polarity/chemotaxis; EC 3.4.24.-; Cell surface; Secreted, signal peptide; Protease
Chromosomal Location of Human Ortholog: 15q24.2
Cellular Component: cell surface; endoplasmic reticulum lumen; proteinaceous extracellular matrix
Molecular Function: metalloendopeptidase activity; metallopeptidase activity; protein binding; zinc ion binding
Biological Process: cellular protein metabolic process; negative regulation of chondrocyte differentiation; post-translational protein modification; protein amino acid O-linked glycosylation; proteolysis involved in cellular protein catabolic process
Research Articles on ADAMTS7
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Product Notes
The Human ADAMTS7 adamts7 (Catalog #AAA2883102) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2883102 ELISA Kit recognizes Human ADAMTS7. It is sometimes possible for the material contained within the vial of "A disintegrin and metalloproteinase with thrombospondin motifs 7, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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