A Disintegrin And Metalloproteinase With Thrombospondin 19 Recombinant Protein | ADAMTS19 recombinant protein

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 19 (ADAMTS19)

Cat. Num. AAA2029381

• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: >95%
• Synonyms: A Disintegrin And Metalloproteinase With Thrombospondin 19; Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 19 (ADAMTS19); ADAMTS19 recombinant protein

• Host: Host: E Coli; Source: Prokaryotic expression
• Purity/Purification: >95%
• Form/Format: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Sequence: The target protein is fused with two N-terminal Tags, His-tag and T7-tag, its sequence is listed below.; YNIETV VVADPAMVSY HGADAARRFI LTILNMVFNL FQHKSLSVQV NLRVIKLILL HETPPELYIG HHGEKMLESF CKWQHEEFGK KNDIHLEMST NWGEDMTSVD AAILITRKDF CVHKDEPCDT VGIAYLSGMC SEKRKCIIAE DNGLNLAFTI AHEMGHNMGI NHDNDHPSCA DGLHIMSGEW IKGQNLGDVS WSRCSKEDLE RFLRSKASNC LLQTNPQSVN SVMVPSKLPG MTYTADEQCQ ILFGPLASFC QEMQHVICTG LWCKVEGEKE CRTKLDPPMD GTDCDLGKWC KAGECTSRTS APEHLAGEWS LWSPCSRTCS AGISSRERKCPGLDSEARDC NGPRKQYRIC ENPPCP
• Sequence Length: 1207

• Applicable Applications for ADAMTS19 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Predicted Molecular Mass: 44.2kDa
• Accurate Molecular Mass (KD): 44kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Expression System: Prokaryotic expression
• Tag: N-terminal His-Tag, T7 tag
• Organism Species: Homo sapiens (Human)
• Fragment: Asp29~Cys252
• Usage: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. The loss of this protein is less than 5% within the expiration date under appropriate storage condition.

Sequence Information

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 112789555
• NCBI GeneID: 171019
• NCBI Accession #: NP_598377.3
• NCBI GenBank Nucleotide #: NM_133638.3
• Molecular Weight: 134,048 Da
• NCBI Official Full Name: A disintegrin and metalloproteinase with thrombospondin motifs 19 preproprotein
• NCBI Official Synonym Full Names: ADAM metallopeptidase with thrombospondin type 1 motif, 19
• NCBI Official Symbol: ADAMTS19
• NCBI Protein Information: A disintegrin and metalloproteinase with thrombospondin motifs 19
• UniProt Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 19
• Protein Family: A disintegrin and metalloproteinase with thrombospondin motifs
• UniProt Gene Name: ADAMTS19
• UniProt Synonym Gene Names: ADAM-TS 19; ADAM-TS19; ADAMTS-19
• UniProt Entry Name: ATS19_HUMAN

NCBI Description

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has high sequence similarity to the protein encoded by ADAMTS16, another family member. [provided by RefSeq, Jul 2008]

Uniprot Description

ADAMTS19:

Protein type: Extracellular matrix; Secreted, signal peptide; Motility/polarity/chemotaxis; Protease; Secreted; EC 3.4.24.-

Chromosomal Location of Human Ortholog: 5q23.3

Cellular Component: proteinaceous extracellular matrix

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: proteolysis