Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human testis tissue using Adrenergic Receptor alpha-2A antibody.)
Adrenergic Receptor alpha-2A Antibody | anti-ADA2A antibody
Adrenergic Receptor alpha-2A Antibody
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:20000
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human testis tissue using Adrenergic Receptor alpha-2A antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human testis tissue using Adrenergic Receptor alpha-2A antibody.)
Western Blot
(Western blot analysis of extracts from LOVO cells and Jurkat cells, using Adrenergic Receptor alpha-2A antibody.)
Western Blot
(Western blot analysis of extracts from LOVO cells and Jurkat cells, using Adrenergic Receptor alpha-2A antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of NIH/3T3 cells, using Adrenergic Receptor alpha-2A antibody.)
Immunofluorescence (IF)
(Immunofluorescence analysis of NIH/3T3 cells, using Adrenergic Receptor alpha-2A antibody.)
NCBI and Uniprot Product Information
NCBI Description
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. Studies in mouse revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons; the alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
Uniprot Description
Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.
Research Articles on ADA2A
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Product Notes
The ADA2A adra2a (Catalog #AAA853934) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Adrenergic Receptor alpha-2A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Adrenergic Receptor alpha-2A can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 IF: 1:100~1:500 ELISA: 1:20000. Researchers should empirically determine the suitability of the ADA2A adra2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Adrenergic Receptor alpha-2A, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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