Rat Activin receptor type-1C ELISA Kit | ACVR1C elisa kit
Rat Activin receptor type-1C (ACVR1C) ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
NCBI and Uniprot Product Information
NCBI Description
may play a role in neuronal maturation [RGD, Feb 2006]
Uniprot Description
ALK7: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.30; Kinase, protein; Membrane protein, integral; Protein kinase, Ser/Thr (receptor); Protein kinase, TKL; STKR family; TKL group; Type1 subfamily
Chromosomal Location of Human Ortholog: 3q21
Cellular Component: activin receptor complex; cell surface; cytoplasm; plasma membrane
Molecular Function: activin binding; activin receptor activity, type I; ATP binding; growth factor binding; metal ion binding; protein serine/threonine kinase activity; signal transducer, downstream of receptor, with serine/threonine kinase activity; SMAD binding
Biological Process: activin receptor signaling pathway; apoptosis; apoptotic nuclear changes; cell differentiation; cerebellum development; determination of left/right symmetry; hippocampus development; in utero embryonic development; lipid storage; midbrain development; negative regulation of insulin secretion; ovarian follicle development; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; protein amino acid phosphorylation; regulation of apoptosis; response to dietary excess; response to drug; response to glucose stimulus; response to insulin stimulus; response to lipid; response to organic cyclic compound; transforming growth factor beta receptor complex assembly
Research Articles on ACVR1C
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Product Notes
The Rat ACVR1C acvr1c (Catalog #AAA281883) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA281883 ELISA Kit recognizes Rat ACVR1C. It is sometimes possible for the material contained within the vial of "Activin receptor type-1C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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