Prolactin, Rat Active Protein | PRL active protein

Prolactin, Recombinant, Rat

Cat. Num. AAA635622

• Purity: Highly Purified; ~95% (SDS-PAGE and HPLC). Endotoxin: <0.1ng/ug.
• Synonyms: Prolactin; Rat; Recombinant; PRL active protein

• Purity/Purification: Highly Purified; ~95% (SDS-PAGE and HPLC). Endotoxin: <0.1ng/ug.
• Form/Format: Supplied as a lyophilized powder from PBS, pH 8. Reconstitute in sterile water to 1mg/ml.

• Biological Activity: The ED50 determined by the dose-dependent stimulation of the proliferation of rat lymphoma, Nb2-11 cells was found to be in the range of 0.1-1.0ng/ml.
• Preparation and Storage: Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

SDS-Page

(Purity of recombinant rat|Prolactin (2ug) was analyzed by|reduced SDS-PAGE|electrophoresis.)

Related Product Information for PRL active protein

Prolactin (also known as mammotrophin, luterotropic hormone, and lutetropin) is a neuroendocrine hormone secreted by the pituitary gland. Its primary function is to promote and

Product Categories/Family for PRL active protein

Molecular Biology; MB-Hormones; Steroids

NCBI and Uniprot Product Information

• NCBI GI #: 254675133
• NCBI GeneID: 5617
• NCBI Accession #: NP_001157030.1
• NCBI GenBank Nucleotide #: NM_001163558.2
• UniProt Accession #: P01236; Q15199; Q92996
• Molecular Weight: ~22.5kD
• NCBI Official Full Name: prolactin
• NCBI Official Synonym Full Names: prolactin
• NCBI Official Symbol: PRL
• NCBI Protein Information: prolactin; decidual prolactin
• UniProt Protein Name: Prolactin
• UniProt Gene Name: PRL
• UniProt Synonym Gene Names: PRL
• UniProt Entry Name: PRL_HUMAN

NCBI Description

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Uniprot Description

prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family.

Protein type: Secreted, signal peptide; Secreted; Motility/polarity/chemotaxis; Cytokine

Chromosomal Location of Human Ortholog: 6p22.3

Cellular Component: extracellular region

Molecular Function: protein binding; prolactin receptor binding; hormone activity

Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy