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Plasminogen Active Protein | PLG active protein

Plasminogen (PLG), Human Plasma

Gene Names
PLG; LPA
Purity
>= 95% (SDS-PAGE)
Synonyms
Plasminogen; Plasminogen (PLG); Human Plasma; PLG; Plasminogen (PLG) - >=95% (SDS-PAGE); PLG active protein
Ordering
For Research Use Only!
Purity/Purification
>= 95% (SDS-PAGE)
Form/Format
Lyophilized
Sequence Length
812
Source
Human Plasma
Unit Definition
Amount of enzyme which hydrolyzes one micromole of N-tosyl-L arginine-methyl ester in 30 minutes at 37 degree C, pH 8.0.
Recertification
2 years
Protein
Reported (A280 E=1.71)
Activity
> 100 U/mg protein
Preparation and Storage
At -20 degree C
Related Product Information for PLG active protein
MyBioSource is a leading supplier of Human Plasma PLASMINOGEN in research and bulk quantities.

Custom preparations, technical support, bulk quantities and aliquoting available.

Plasmin is released as a zymogen called PLASMINOGEN (PLG) from the liver into the systemic circulation. Two major glycoforms of plasminogen are present in humans - type I plasminogen contains two glycosylation moieties (N-linked to N289 and O-linked to T346), whereas type II plasminogen contains only a single O-linked sugar (O-linked to T346). Type II plasminogen is preferentially recruited to the cell surface over the type I glycoform. Conversely, type I plasminogen appears more readily recruited to blood clots.
Product Categories/Family for PLG active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
91,216 Da
NCBI Official Full Name
plasminogen
NCBI Official Symbol
PLG
NCBI Official Synonym Symbols
LPA
NCBI Protein Information
plasminogen; lipoprotein, Lp(a)
UniProt Protein Name
Plasminogen
Protein Family
UniProt Gene Name
PLG
UniProt Entry Name
PLMN_BOVIN

Uniprot Description

Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells ().

Research Articles on PLG

Similar Products

Product Notes

The PLG plg (Catalog #AAA173563) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Plasminogen, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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