Growth and Differentiation Factor 5 Active Protein | Gdf5 active protein
Growth and Differentiation Factor 5, Recombinant, Human (GDF-5)
Gene Names
Gdf5; Cdmp1
Purity
Highly Purified~95% (SDS-PAGE and HPLC). Endotoxin: <0.1ng/ug.
Synonyms
Growth and Differentiation Factor 5; Recombinant; Human (GDF-5); Gdf5 active protein
Purity/Purification
Highly Purified
~95% (SDS-PAGE and HPLC). Endotoxin: <0.1ng/ug.
~95% (SDS-PAGE and HPLC). Endotoxin: <0.1ng/ug.
Form/Format
Supplied as a lyophilized powder. No additives added. Reconstitute in 20mM HOAc to 0.1-1.0mg/ml.
Biological Activity
The biological activity of the protein was measured by induction of alkaline phosphatase activity in ATDC5 cells. The EC50 is 30-50nM.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with 20mM HOAc. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Gdf5 active protein
GDF-5 acts as an inhibitor of nerve tissue growth. It is produced as a homodimer, nonglycosylated polypeptide chain containing 2X117aa with a molecular weight of 26.8kD. To enable bacterial expression of rhGDF-5 we removed the N-terminal sequence Ala-Pro-Leu-Thr and added the Lys.
Product Categories/Family for Gdf5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
~26.8kD
NCBI Official Full Name
growth and differentiation factor-5
NCBI Official Synonym Full Names
growth differentiation factor 5
NCBI Official Symbol
Gdf5
NCBI Official Synonym Symbols
Cdmp1
NCBI Protein Information
growth differentiation factor 5; cartilage-derived morphogenetic protein 1
UniProt Protein Name
Growth and differentiation factor-5
Protein Family
UniProt Gene Name
Gdf5
UniProt Synonym Gene Names
gdf-5
UniProt Entry Name
Q5KSY1_RAT
NCBI Description
member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily; regulates cell growth and differentiation; involved with tendon and ligament formation [RGD]
Uniprot Description
Sequence similarities: Belongs to the TGF-beta family. RuleBase RU000354
Research Articles on Gdf5
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Product Notes
The Gdf5 gdf5 (Catalog #AAA650140) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Growth and Differentiation Factor 5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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