SDS-Page
(SDS-PAGE, The approximate molecular weight is 82kD and the average purity is 95%.)
Chk1, active Active Protein
Chk1, active, Recombinant, Human (CHEK1, Cell Cycle Checkpoint Kinase)
Purity
Highly Purified95% by densitometry
Synonyms
Chk1; active; Recombinant; Human (CHEK1; Cell Cycle Checkpoint Kinase); active active protein
Purity/Purification
Highly Purified
95% by densitometry
95% by densitometry
Form/Format
Supplied as a liquid in 50mM Tris-HCl, pH 7.5, 150mM sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Activity
The specific activity of Chk1 was determined to be 195 nmol/min/mg using a synthetic peptide substrate (KKKVSRSGLYRSPSMPENLNRPR).
Preparation and Storage
This product is stable at -70 degree C for at least 6 months from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
SDS-Page
(SDS-PAGE, The approximate molecular weight is 82kD and the average purity is 95%.)
SDS-Page
(SDS-PAGE, The approximate molecular weight is 82kD and the average purity is 95%.)
Related Product Information for Chk1, active active protein
Chk1 is a 56kD Serine/Threonine protein kinase that was originally identified in fission yeast to play a role in activation of the DNA damage checkpoint in the G2 phase of the cell cycle (1). Chk1 appears to function downstream of several of the known fission yeast checkpoint gene products, including that encoded by Rad3, a gene with sequence similarity to the ATM gene mutated in patients with ataxia telangiectasia (2).
Product Categories/Family for Chk1, active active protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
The approximate molecular weight is 82kD (see Figure 1 below).
NCBI Official Full Name
Chain A, Crystal Structure Of Checkpoint Kinase 1 (Chk1) In Complex With Inhibitors
Similar Products
Product Notes
The Chk1, active (Catalog #AAA637244) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Chk1, active, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
