BMP13 active protein
BMP13 protein
Applications
User optimized
Purity
> 95% by SDS-PAGE
Synonyms
BMP13; BMP13 protein; BMP-13 protein; BMP-13; BMP 13; CDMP-2 protein; Cartilage-Derived Morphogenetic Protein-2 protein; Bone Morphogenetic protein 13 protein; GDF-6 protein; BMP 13 protein; BMP13 active protein
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Supplied lyophilized with no additives. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex.
Concentration
50ug per vial; lyophilized (varies by lot)
Sequence
Region of BMP13 protein corresponding to amino acids TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR.
Applicable Applications for BMP13 active protein
User optimized
Application Notes
The expected ED50 for this effect is 2.0-3.0 ug/ml.
Protein Type
Recombinant
Biological Significance
BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains.
Bioactivity
The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 ug/ml.
Endotoxin Levels
Endotoxin level is less than 0.1ng/ug of protein.
Source
E Coli
Species
Human
Grade
Recombinant
Biohazard
Use standard laboratory precautions when handling this material.
Preparation and Storage
Ships ambient or refrigerated. Upon receipt, store at 4 degree C or -20 degree C. After reconstitution, store at 4 degree C for one week, or aliquot and freeze at -20 degree C or -80 degree C. For extended storage, further dilute in a buffer containing a carrier protein and freeze.
Related Product Information for BMP13 active protein
Purified recombinant Human BMP13 protein
Product Categories/Family for BMP13 active protein
Similar Products
Product Notes
The BMP13 (Catalog #AAA538258) is an Active Protein and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's BMP13 can be used in a range of immunoassay formats including, but not limited to, User optimized. The expected ED50 for this effect is 2.0-3.0 ug/ml. Researchers should empirically determine the suitability of the BMP13 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Region of BMP13 protein correspond ing to amino acids TAFASRHGKR HGKKSRLRCS KKPLHVNFKE LGWDDWIIAP LEYEAYHCEG VCDFPLRSHL EPTNHAIIQT LMNSMDPGST PPSCCVPTKL TPISILYIDA GNNVVYKQYE DMVVESCGCR. It is sometimes possible for the material contained within the vial of "BMP13, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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