Acyl-coenzyme A thioesterase 13 (ACOT13) Recombinant Protein | ACOT13 recombinant protein

Recombinant Human Acyl-coenzyme A thioesterase 13 (ACOT13)

Cat. Num. AAA1365124

• Gene Names: ACOT13; HT012; THEM2; PNAS-27
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Acyl-coenzyme A thioesterase 13 (ACOT13); Recombinant Human Acyl-coenzyme A thioesterase 13 (ACOT13); ACOT13 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-140, Full length protein
• Sequence: MTSMTQSLREVIKAMTKARNFERVLGKITLVSAAPGKVICEMKVEEEHTNAIGTLHGGLTATLVDNISTMALLCTERGAPGVSVDMNITYMSPAKLGEDIVITAHVLKQGKTLAFTSVDLTNKATGKLIAQGRHTKHLGN
• Sequence Length: 140

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 231567183
• NCBI GeneID: 55856
• NCBI Accession #: NP_001153566.1
• NCBI GenBank Nucleotide #: NM_001160094.1
• UniProt Accession #: Q9NPJ3; O95549; F5H2L4
• Molecular Weight: 12,366 Da
• NCBI Official Full Name: acyl-coenzyme A thioesterase 13 isoform 2
• NCBI Official Synonym Full Names: acyl-CoA thioesterase 13
• NCBI Official Symbol: ACOT13
• NCBI Official Synonym Symbols: HT012; THEM2; PNAS-27
• NCBI Protein Information: acyl-coenzyme A thioesterase 13
• UniProt Protein Name: Acyl-coenzyme A thioesterase 13
• Protein Family: Acyl-coenzyme A thioesterase
• UniProt Gene Name: ACOT13
• UniProt Synonym Gene Names: THEM2; Acyl-CoA thioesterase 13

NCBI Description

This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009]

Uniprot Description

Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA and 3,4-dihydroxyphenylacetyl-CoA (in vitro). May play a role in controlling adaptive thermogenesis ().