ATP-binding cassette sub-family B member 7, mitochondrial (ABCB7) Recombinant Protein | ABCB7 recombinant protein

Recombinant Human ATP-binding cassette sub-family B member 7, mitochondrial (ABCB7), partial

Cat. Num. AAA1199909

• Gene Names: ABCB7; ABC7; ASAT; Atm1p; EST140535
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: ATP-binding cassette sub-family B member 7; mitochondrial (ABCB7); Recombinant Human ATP-binding cassette sub-family B member 7; partial; ABCB7 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 141-161
• Sequence: AISLGFLGGAKAMNIVVPFMF
• Sequence Length: 753

• Species: Homo sapiens (Human)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 411147363
• NCBI GeneID: 22
• NCBI Accession #: NP_001258625.1
• NCBI GenBank Nucleotide #: NM_001271696.2
• UniProt Accession #: O75027; O75345; Q5VWY7; Q5VWY8; Q9BRE1; Q9UND1; Q9UP01; G3XAC4
• Molecular Weight: 78,160 Da
• NCBI Official Full Name: ATP-binding cassette sub-family B member 7, mitochondrial isoform 2
• NCBI Official Synonym Full Names: ATP binding cassette subfamily B member 7
• NCBI Official Symbol: ABCB7
• NCBI Official Synonym Symbols: ABC7; ASAT; Atm1p; EST140535
• NCBI Protein Information: ATP-binding cassette sub-family B member 7, mitochondrial
• UniProt Protein Name: ATP-binding cassette sub-family B member 7, mitochondrial
• Protein Family: ABC transporter B family
• UniProt Gene Name: ABCB7
• UniProt Synonym Gene Names: ABC7; ABC transporter 7 protein

NCBI Description

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

Uniprot Description

Could be involved in the transport of heme from the mitochondria to the cytosol. Plays a central role in the maturation of cytosolic iron-sulfur (Fe/S) cluster-containing proteins.