Rat ATP-binding cassette, sub-family B (MDR/TAP) , member 4 ELISA Kit | ABCB4 elisa kit
Rat Multidrug resistance protein 3, ABCB4 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
energy-dependent efflux pump; may be involved in changes in bile formation in response to diabetes [RGD, Feb 2006]
Uniprot Description
ABCB4: a transporter that mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Human ABCB4 is not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte. Interacts with HAX1. Defects are the cause of gallstones, and progressive familial intrahepatic cholestasis 3, an autosomal recessive liver disorder that progresses to cirrhosis and liver failure before adulthood. Two alternatively spliced human isoforms have been described.
Protein type: Hydrolase; Membrane protein, multi-pass; EC 3.6.3.44; Transporter, ABC family; Membrane protein, integral; Transporter
Cellular Component: Golgi membrane; intercellular canaliculus; membrane; apical plasma membrane; integral to membrane
Molecular Function: protein binding; ATPase activity, coupled to transmembrane movement of substances; xenobiotic-transporting ATPase activity; ATP binding
Biological Process: response to drug; metabolic process; response to glucocorticoid stimulus; multidrug transport; xenobiotic transport; transmembrane transport
Research Articles on ABCB4
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Product Notes
The Rat ABCB4 abcb4 (Catalog #AAA9324122) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9324122 ELISA Kit recognizes Rat ABCB4. It is sometimes possible for the material contained within the vial of "ATP-binding cassette, sub-family B (MDR/TAP) , member 4, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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