Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Transforming growth factor beta receptor type 3 (TGFBR3) Standard Curve.)
Mouse Transforming Growth Factor beta Receptor Type 3 (TGFBR3) ELISA Kit | TGFBR3 elisa kit
Mouse Transforming Growth Factor beta Receptor Type 3 (TGFBR3) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Transforming growth factor beta receptor type 3 (TGFBR3) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Mouse Transforming growth factor beta receptor type 3 (TGFBR3) Standard Curve.)
Background: This locus TGFBR3 encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for TGFBR3.
NCBI and Uniprot Product Information
Uniprot Description
TGFBR3: Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors. Interacts with TCTEX1D4. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral
Cellular Component: proteinaceous extracellular matrix; extracellular space; cell surface; membrane; endoplasmic reticulum; integral to plasma membrane; cytoplasm; extracellular region; integral to membrane; plasma membrane; receptor complex; external side of plasma membrane
Molecular Function: heparin binding; transforming growth factor beta receptor activity; protein binding; fibroblast growth factor binding; glycosaminoglycan binding; transforming growth factor beta binding; punt binding; activin binding; coreceptor activity; SMAD binding; transforming growth factor beta receptor binding; PDZ domain binding
Biological Process: transforming growth factor beta receptor complex assembly; blood vessel development; blastocyst development; in utero embryonic development; positive regulation of transforming growth factor beta receptor signaling pathway; negative regulation of cell motility; cardiac muscle cell proliferation; palate development; liver development; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; BMP signaling pathway; embryonic development; regulation of protein binding; transforming growth factor beta receptor signaling pathway; epithelial to mesenchymal transition; ventricular cardiac muscle morphogenesis; immune response; protein complex assembly; cell growth; regulation of blood vessel size; negative regulation of transforming growth factor beta receptor signaling pathway; response to follicle-stimulating hormone stimulus; negative regulation of epithelial cell proliferation
Research Articles on TGFBR3
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Product Notes
The Mouse TGFBR3 tgfbr3 (Catalog #AAA9716982) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716982 ELISA Kit recognizes Mouse TGFBR3. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor beta Receptor Type 3 (TGFBR3), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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