Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ribonuclease P protein subunit p29 (POP4) Standard Curve.)
Human Ribonuclease P Protein Subunit p29 (POP4) ELISA Kit | POP4 elisa kit
Human Ribonuclease P Protein Subunit p29 (POP4) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ribonuclease P protein subunit p29 (POP4) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Ribonuclease P protein subunit p29 (POP4) Standard Curve.)
Background: POP4 encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants.The deduced 220-amino acid basic protein is rich in arginine and lysine, has nuclear localization sequences, and has a predicted molecular mass of approximately 25 kD. RPP29 is 23% identical to the yeast Pop4 protein. Fluorescent microscopy demonstrated nuclear and nucleolar expression of RPP29. Immunoblot analysis showed that antibodies to RPP14 or RPP29 precipitate native RNase P.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]
Uniprot Description
POP4: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. Belongs to the eukaryotic/archaeal RNase P protein component 1 family.
Protein type: Ribonuclease; RNA-binding; RNA processing; Nucleolus; EC 3.1.26.5
Chromosomal Location of Human Ortholog: 19q12
Cellular Component: nucleolar ribonuclease P complex; ribonuclease MRP complex; ribonuclease P complex
Molecular Function: protein binding; RNA binding; ribonuclease MRP activity; ribonuclease P activity; ribonuclease P RNA binding
Biological Process: tRNA processing; rRNA processing; mRNA cleavage
Research Articles on POP4
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Product Notes
The Human POP4 pop4 (Catalog #AAA9716011) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9716011 ELISA Kit recognizes Human POP4. It is sometimes possible for the material contained within the vial of "Ribonuclease P Protein Subunit p29 (POP4), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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