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Western Blot (WB) (Western Blot analysis of extracts of various cells, using POP4 antibody.)

Rabbit POP4 Polyclonal Antibody | anti-POP4 antibody

POP4 Polyclonal Antibody

Gene Names
POP4; RPP29
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Synonyms
POP4; Polyclonal Antibody; POP4 Polyclonal Antibody; RPP29; anti-POP4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
POP4 polyclonal antibody detects endogenous levels of POP4 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is >95% (by SDS-PAGE).
Form/Format
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Sequence Length
220
Applicable Applications for anti-POP4 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:200-1:2000
IHC: 1:50-1:200
Immunogen
Recombinant protein of human POP4.
Preparation and Storage
Store at 4 degree C short term.
Aliquot and store at -20 degree C long term.
Avoid freeze-thaw cycles.

Western Blot (WB)

(Western Blot analysis of extracts of various cells, using POP4 antibody.)

Western Blot (WB) (Western Blot analysis of extracts of various cells, using POP4 antibody.)
Related Product Information for anti-POP4 antibody
This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
~ 25kDa
NCBI Official Full Name
ribonuclease P protein subunit p29
NCBI Official Synonym Full Names
POP4 homolog, ribonuclease P/MRP subunit
NCBI Official Symbol
POP4
NCBI Official Synonym Symbols
RPP29
NCBI Protein Information
ribonuclease P protein subunit p29
UniProt Protein Name
Ribonuclease P protein subunit p29
Protein Family
UniProt Gene Name
POP4
UniProt Synonym Gene Names
RPP29; hPOP4
UniProt Entry Name
RPP29_HUMAN

NCBI Description

This gene encodes one of the protein subunits of the small nucleolar ribonucleoprotein complexes: the endoribonuclease for mitochondrial RNA processing complex and the ribonuclease P complex. The encoded protein is localized to the nucleus and associates directly with the RNA component of these complexes. This protein is involved in processing of precursor RNAs. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009]

Uniprot Description

POP4: Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. May function with RPP38 to coordinate the nucleolar targeting and/or assembly of RNase P. Belongs to the eukaryotic/archaeal RNase P protein component 1 family.

Protein type: Ribonuclease; RNA-binding; RNA processing; Nucleolus; EC 3.1.26.5

Chromosomal Location of Human Ortholog: 19q12

Cellular Component: nucleolar ribonuclease P complex; ribonuclease MRP complex; ribonuclease P complex

Molecular Function: protein binding; RNA binding; ribonuclease MRP activity; ribonuclease P activity; ribonuclease P RNA binding

Biological Process: tRNA processing; rRNA processing; mRNA cleavage

Research Articles on POP4

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Product Notes

The POP4 pop4 (Catalog #AAA3008606) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POP4 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's POP4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:200-1:2000 IHC: 1:50-1:200. Researchers should empirically determine the suitability of the POP4 pop4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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