Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-1 (TMOD1) Standard Curve.)
Human Tropomodulin-1 (TMOD1) ELISA Kit | TMOD1 elisa kit
Human Tropomodulin-1 (TMOD1) ELISA Kit
Gene Names
TMOD1; TMOD; ETMOD; D9S57E
Reactivity
Human
Synonyms
Tropomodulin-1 (TMOD1); Human Tropomodulin-1 (TMOD1) ELISA Kit; TMOD1; D9S57E; ETMOD; TMOD; OTTHUMP00000021743; e-tropomodulin; erythrocyte tropomodulin; TMOD1 elisa kit
Reactivity
Human
Specificity
Human Tropomodulin-1 (TMOD1) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMOD1. No significant cross-reactivity or interference between Human TMOD1 and analogues was observed.
Sequence Length
359
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-1 (TMOD1) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-1 (TMOD1) Standard Curve.)
Related Product Information for TMOD1 elisa kit
Description: This Human Tropomodulin-1 (TMOD1) ELISA Kit employs a two-site sandwich ELISA to quantitate TMOD1 in samples. An antibody specific for TMOD1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TMOD1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TMOD1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TMOD1 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: TMOD1 encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. TMOD gene is expressed in major human tissues at different levels in the following order: heart and skeletal muscle much greater than in brain, lung, and pancreas, which is greater than in placenta, liver, and kidney. They pointed to structural similarities between tropomodulin and the 64-kD autoantigen in Graves disease and suggested that the 2 genes evolved from a common ancestral gene.
Background: TMOD1 encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. TMOD gene is expressed in major human tissues at different levels in the following order: heart and skeletal muscle much greater than in brain, lung, and pancreas, which is greater than in placenta, liver, and kidney. They pointed to structural similarities between tropomodulin and the 64-kD autoantigen in Graves disease and suggested that the 2 genes evolved from a common ancestral gene.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
tropomodulin-1
NCBI Official Synonym Full Names
tropomodulin 1
NCBI Official Symbol
TMOD1
NCBI Official Synonym Symbols
TMOD; ETMOD; D9S57E
NCBI Protein Information
tropomodulin-1
UniProt Protein Name
Tropomodulin-1
Protein Family
UniProt Gene Name
TMOD1
UniProt Synonym Gene Names
D9S57E; TMOD; E-Tmod
UniProt Entry Name
TMOD1_HUMAN
NCBI Description
This gene encodes a member of the tropomodulin family. The encoded protein is an actin-capping protein that regulates tropomyosin by binding to its N-terminus, inhibiting depolymerization and elongation of the pointed end of actin filaments and thereby influencing the structure of the erythrocyte membrane skeleton. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2009]
Research Articles on TMOD1
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Product Notes
The Human TMOD1 tmod1 (Catalog #AAA9713924) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9713924 ELISA Kit recognizes Human TMOD1. It is sometimes possible for the material contained within the vial of "Tropomodulin-1 (TMOD1), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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