Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Transforming growth factor beta1 receptor (TGF-beta1R) Standard Curve.)
Rat Transforming Growth Factor beta1 Receptor (TGF-beta1R) ELISA Kit | TGF-beta1R elisa kit
Rat Transforming Growth Factor beta1 Receptor (TGF-beta1R) ELISA Kit
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Transforming growth factor beta1 receptor (TGF-beta1R) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Rat Transforming growth factor beta1 receptor (TGF-beta1R) Standard Curve.)
Background: The protein encoded by TGF-beta1R gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase.
NCBI and Uniprot Product Information
NCBI Description
forms a heteromeric receptor complex with TGF-beta type II receptor that binds TGF-beta and mediates TGF-beta signalling [RGD, Feb 2006]
Uniprot Description
TGFBR1: a TKL kinase of the serine/threonine-protein kinase receptor (STKR) family. R1 and R2 TGF-beta receptors dimerize after binding TGF-beta at the cell surface. Found in all tissues; most abundant in placenta and least abundant in brain and heart.
Protein type: Membrane protein, integral; Receptor, misc.; EC 2.7.11.30; Protein kinase, TKL; Protein kinase, Ser/Thr (receptor); Kinase, protein; TKL group; STKR family; Type1 subfamily
Cellular Component: apical plasma membrane; basolateral plasma membrane; caveola; cell; cell surface; endosome; integral to membrane; intracellular; lipid raft; membrane; plasma membrane; protein complex; receptor complex; tight junction
Molecular Function: ATP binding; growth factor binding; metal ion binding; protein complex binding; protein heterodimerization activity; protein kinase activity; protein serine/threonine kinase activity; punt binding; receptor binding; receptor signaling protein activity; receptor signaling protein serine/threonine kinase activity; SMAD binding; transforming growth factor beta binding; transforming growth factor beta receptor activity; transforming growth factor beta receptor activity, type I; ubiquitin protein ligase binding
Biological Process: activation of MAPKK activity; activin receptor signaling pathway; aging; angiogenesis; anterior/posterior pattern formation; apoptosis; artery morphogenesis; blastocyst development; cell motility involved in cell locomotion; collagen fibril organization; embryo implantation; embryonic cranial skeleton morphogenesis; endothelial cell activation; endothelial cell migration; epithelial to mesenchymal transition; germ cell migration; gut development; heart development; in utero embryonic development; kidney development; lens development in camera-type eye; lung development; male gonad development; mesenchymal cell differentiation; negative regulation of apoptosis; negative regulation of chondrocyte differentiation; negative regulation of endothelial cell differentiation; negative regulation of endothelial cell proliferation; neuron fate commitment; organ regeneration; palate development; parathyroid gland development; peptidyl-serine phosphorylation; peptidyl-threonine phosphorylation; pharyngeal system development; positive regulation of cell growth; positive regulation of cell migration; positive regulation of cell motility; positive regulation of cell proliferation; positive regulation of endothelial cell proliferation; positive regulation of filopodium formation; positive regulation of protein kinase B signaling cascade; positive regulation of transcription, DNA-dependent; post-embryonic development; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of gene expression; regulation of growth; regulation of protein binding; regulation of protein ubiquitination; regulation of transcription, DNA-dependent; response to electrical stimulus; response to estrogen stimulus; response to hypoxia; response to organic cyclic substance; response to toxin; signal transduction; skeletal development; skeletal morphogenesis; thymus development; transforming growth factor beta receptor signaling pathway
Research Articles on TGF-beta1R
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Product Notes
The Rat TGF-beta1R tgfbr1 (Catalog #AAA9711824) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9711824 ELISA Kit recognizes Rat TGF-beta1R. It is sometimes possible for the material contained within the vial of "Transforming Growth Factor beta1 Receptor (TGF-beta1R), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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